Revision as of 11:17, 14 May 2013

Description: membrane protein

Gene name	sdpB
Synonyms	yvaX
Essential	no
Product	unknown
Function	unknown
*Gene expression levels in SubtiExpress*: sdpB
MW, pI	37 kDa, 9.521
Gene length, protein length	969 bp, 323 aa
Immediate neighbours	sdpA, sdpC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance PubMed

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, membrane proteins

This gene is a member of the following regulons

AbrB regulon, Rok regulon, Spo0A regulon

The gene

Basic information

Locus tag: BSU33760

Phenotypes of a mutant

Database entries

DBTBS entry: [1]

SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

Catalyzed reaction/ biological activity:

Protein family:

Paralogous protein(s):

Extended information on the protein

Kinetic information:

Domains:

Modification:

Cofactor(s):

Effectors of protein activity:

Interactions:

Localization:
- cell membrane PubMed

Database entries

Structure:

UniProt: O34616

KEGG entry: [3]

E.C. number:

Additional information

Expression and regulation

Operon: sdpA-sdpB-sdpC PubMed

Expression browser: sdpB PubMed

Sigma factor:

Regulation:
- expressed under conditions that trigger sporulation (Spo0A) PubMed
- repressed by Rok PubMed
- repressed during logrithmic growth (AbrB) PubMed
- strongly repressed in response to glucose starvation in M9 medium PubMed

Regulatory mechanism:
- Spo0A: transcription activation PubMed
- Rok: transcription repression PubMed
- AbrB: transcription repression PubMed

Additional information:
- the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed

Biological materials

Mutant:

Expression vector:

lacZ fusion:

GFP fusion:

two-hybrid system:

Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original Publications

Additional publications: PubMed

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947

@@ Line 22: / Line 22: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sdpA]]'', ''[[sdpC]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU33760 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU33760 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU33760 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU33760 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU33760 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU33760 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:yvaX_context.gif]]