Revision as of 13:15, 13 May 2013

Description: DNA repair and genetic recombination

Gene name	recN
Synonyms
Essential	no
Product	unknown
Function	DNA repair and genetic recombination
*Gene expression levels in SubtiExpress*: recN
MW, pI	64 kDa, 4.802
Gene length, protein length	1728 bp, 576 aa
Immediate neighbours	spoIVB, ahrC
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance PubMed

Categories containing this gene/protein

DNA repair/ recombination, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

Locus tag: BSU24240

Phenotypes of a mutant

Database entries

DBTBS entry: [1]

SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

Catalyzed reaction/ biological activity:
- RecN stimulates polymerizing activity of PnpA PubMed

Protein family: recN family (according to Swiss-Prot)

Paralogous protein(s):

Extended information on the protein

Kinetic information:

Domains:

Modification:

Cofactor(s):

Effectors of protein activity:

Interactions:

Localization:
- nucleoid (Multiple) PubMed
- evenly distributed in growing cells PubMed
- upon DNA damage, RecN forms a single focus per nucleoid PubMed

Database entries

Structure:

UniProt: P17894

KEGG entry: [3]

E.C. number:

Additional information

Expression and regulation

Operon: ahrC-recN PubMed

Expression browser: recN PubMed

Sigma factor:

Regulation:

Regulatory mechanism:

Additional information:

Biological materials

Mutant:
- 1A891 ( recN::cat), PubMed, available at BGSC

Expression vector:

lacZ fusion:

GFP fusion:

two-hybrid system:

Antibody:

Labs working on this gene/protein

Peter Graumann, Freiburg University, Germany homepage

Your additional remarks

References

Reviews

Additional reviews: PubMed <pubmed>19308706 21517913</pubmed>

Original publications

Additional publications: PubMed <pubmed>15849320,19060143,16385024,17999999,2106508,19730681 ,16479537 </pubmed>

@@ Line 14: / Line 14: @@
 |style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair and genetic recombination
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU24240 recN]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU24240 recN]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 64 kDa, 4.802
@@ Line 22: / Line 22: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIVB]]'', ''[[ahrC]]''
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14355&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU24240 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU24240 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU24240 Advanced_DNA]
 |-
 |-