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* '''Regulation:'''  
* '''Regulation:'''  
** repressed by phosphate ([[PhoP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9457886 PubMed]
** repressed by phosphate ([[PhoP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9457886 PubMed]
** strongly repressed in response to glucose starvation in M9 medium {{PubMed|23033921}}


* '''Regulatory mechanism:'''  
* '''Regulatory mechanism:'''  
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=References=
=References=
 
'''Additional publications:''' {{PubMed|23033921}}
<pubmed>18156271,16141206 2507871 ,12637499,1712357,9457886,18763711, 19520862 7581998 12950927 15547257 </pubmed>
<pubmed>18156271,16141206 2507871 ,12637499,1712357,9457886,18763711, 19520862 7581998 12950927 15547257 </pubmed>


[[Category:Protein-coding genes]]
[[Category:Protein-coding genes]]

Revision as of 19:42, 8 October 2012

  • Description: CDP-glycerol:polyglycerol phosphate glycero-phosphotransferase

Gene name tagF
Synonyms rodC
Essential yes PubMed
Product CDP-glycerol:polyglycerol phosphate glycero-phosphotransferase
Function biosynthesis of teichoic acid
Gene expression levels in SubtiExpress: tagF
MW, pI 87 kDa, 9.4
Gene length, protein length 2238 bp, 746 aa
Immediate neighbours tagG, tagE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
This image was kindly provided by SubtiList
Expression at a glance   PubMed















Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, essential genes, membrane proteins

This gene is a member of the following regulons

PhoP regulon, WalR regulon

The gene

Basic information

  • Locus tag: BSU35720

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: CDP-glycerol + (glycerophosphate)(n) = CMP + (glycerophosphate)(n+1) (according to Swiss-Prot)
  • Protein family: CDP-glycerol glycerophosphotransferase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed by phosphate (PhoP) PubMed
    • strongly repressed in response to glucose starvation in M9 medium PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed <pubmed>18156271,16141206 2507871 ,12637499,1712357,9457886,18763711, 19520862 7581998 12950927 15547257 </pubmed>