BdbB: Difference between revisions
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* '''Description:''' thiol-disulfide oxidoreductase <br/><br/> | |||
{| align="right" border="1" cellpadding="2" | |||
|- | |||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |||
|''bdbB'' | |||
|- | |||
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yolK '' | |||
|- | |||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |||
|- | |||
|style="background:#ABCDEF;" align="center"| '''Product''' || thiol-disulfide oxidoreductase | |||
|- | |||
|style="background:#ABCDEF;" align="center"|'''Function''' || oxidative folding of proteins | |||
|- | |||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU21440 bdbB] | |||
|- | |||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]''' | |||
|- | |||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 9.415 | |||
|- | |||
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 444 bp, 148 aa | |||
|- | |||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[bhlB]]'', ''[[sunS]]'' | |||
|- | |||
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB14062]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | |||
|- | |||
|colspan="2" | '''Genetic context''' <br/> [[Image:bdbB_context.gif]] | |||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | |||
|- | |||
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=bdbB_2265225_2265671_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:bdbB_expression.png|500px]] | |||
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|} | |||
__TOC__ | |||
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= [[Categories]] containing this gene/protein = | |||
{{SubtiWiki category|[[chaperones/ protein folding]]}}, | |||
{{SubtiWiki category|[[SP-beta prophage]]}}, | |||
{{SubtiWiki category|[[membrane proteins]]}} | |||
= This gene is a member of the following [[regulons]] = | |||
{{SubtiWiki regulon|[[Abh regulon]]}}, | |||
{{SubtiWiki regulon|[[AbrB regulon]]}}, | |||
{{SubtiWiki regulon|[[Rok regulon]]}}, | |||
{{SubtiWiki regulon|[[YvrHb regulon]]}} | |||
=The gene= | |||
=== Basic information === | |||
* '''Locus tag:''' BSU21440 | |||
===Phenotypes of a mutant === | |||
=== Database entries === | |||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sunT-bdbA-yolJ-bdbB.html] | |||
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13587] | |||
=== Additional information=== | |||
=The protein= | |||
=== Basic information/ Evolution === | |||
* '''Catalyzed reaction/ biological activity:''' | |||
** oxidative folding of [[SunA]] (together with [[BdbC]]) | |||
* '''Protein family:''' NAD-dependent glycerol-3-phosphate dehydrogenase family (according to Swiss-Prot) | |||
* '''Paralogous protein(s):''' | |||
=== Extended information on the protein === | |||
* '''Kinetic information:''' | |||
* '''Domains:''' | |||
* '''Modification:''' | |||
* '''Cofactor(s):''' | |||
* '''Effectors of protein activity:''' | |||
* '''[[SubtInteract|Interactions]]:''' | |||
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot) | |||
=== Database entries === | |||
* '''Structure:''' | |||
* '''UniProt:''' [http://www.uniprot.org/uniprot/P68571 P68571] | |||
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU21440] | |||
* '''E.C. number:''' | |||
=== Additional information=== | |||
=Expression and regulation= | |||
** '''Operon:''' ''[[sunT]]-[[bdbA]]-[[sunS]]-[[bdbB]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed] | |||
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=bdbB_2265225_2265671_-1 bdbB] {{PubMed|22383849}} | |||
* '''Sigma factor:''' | |||
* '''Regulation:''' | |||
** repressed by [[Rok]] [http://www.ncbi.nlm.nih.gov/sites/entrez/15743949 PubMed] | |||
* '''Regulatory mechanism:''' | |||
** activated by [[YvrHb]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed] | |||
** [[Rok]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/15743949 PubMed] | |||
** [[AbrB]]: transcription repression{{PubMed|20817675}} | |||
** [[Abh]]: transcription activation {{PubMed|20817675}} | |||
* '''Additional information:''' | |||
=Biological materials = | |||
* '''Mutant:''' | |||
* '''Expression vector:''' | |||
* '''lacZ fusion:''' | |||
* '''GFP fusion:''' | |||
* '''two-hybrid system:''' | |||
* '''Antibody:''' | |||
=Labs working on this gene/protein= | |||
=Your additional remarks= | |||
=References= | |||
'''Additional publications:''' {{PubMed|20817675}} | |||
<pubmed>11872755 15743949, </pubmed> | |||
[[Category:Protein-coding genes]] | |||
Revision as of 20:14, 8 August 2012
- Description: thiol-disulfide oxidoreductase
| Gene name | bdbB |
| Synonyms | yolK |
| Essential | no |
| Product | thiol-disulfide oxidoreductase |
| Function | oxidative folding of proteins |
| Gene expression levels in SubtiExpress: bdbB | |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 16 kDa, 9.415 |
| Gene length, protein length | 444 bp, 148 aa |
| Immediate neighbours | bhlB, sunS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Categories containing this gene/protein
chaperones/ protein folding, SP-beta prophage, membrane proteins
This gene is a member of the following regulons
Abh regulon, AbrB regulon, Rok regulon, YvrHb regulon
The gene
Basic information
- Locus tag: BSU21440
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: NAD-dependent glycerol-3-phosphate dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P68571
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed <pubmed>11872755 15743949, </pubmed>