LctP

• Description: lactate permease, excretion
  
  

Gene name	lctP
Synonyms	ycgC
Essential	no
Product	L-lactate permease
Function	lactate excretion
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism
MW, pI	57 kDa, 9.766
Gene length, protein length	1623 bp, 541 aa
Immediate neighbours	ldh, mdr
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, carbon core metabolism, membrane proteins

This gene is a member of the following regulons

Rex regulon

The gene

Basic information

• Locus tag: BSU03060

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: lactate permease family (according to Swiss-Prot)

• Paralogous protein(s): LutP

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P55910

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ldh-lctP PubMed

• Expression browser: lctP PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced under anaerobic conditions (Rex) PubMed

• Regulatory mechanism:
  • Rex: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed>16207915,10809684 16428414 ,17573341 , </pubmed>