LutB: Difference between revisions
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
no growth with lactate as the single carbon source | no growth with lactate as the single carbon source [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed] | ||
=== Database entries === | === Database entries === | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
* '''Catalyzed reaction/ biological activity:''' oxidation of lactate to pyruvate | * '''Catalyzed reaction/ biological activity:''' oxidation of lactate to pyruvate [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed] | ||
* '''Protein family:''' | * '''Protein family:''' | ||
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=Expression and regulation= | =Expression and regulation= | ||
* '''Operon:''' ''[[lutA]]-[[lutB]]-[[lutC]]'' | * '''Operon:''' ''[[lutA]]-[[lutB]]-[[lutC]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed] | ||
* '''Sigma factor:''' | * '''Sigma factor:''' | ||
* '''Regulation:''' induction by lactate | * '''Regulation:''' induction by lactate [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed] | ||
* '''Regulatory mechanism:''' dual repression by [[LutR]] (inducer lactate) and [[SinR]] | * '''Regulatory mechanism:''' dual repression by [[LutR]] (inducer lactate) and [[SinR]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed] | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 15:45, 10 February 2009
- Description: lactate catabolic enzyme
| Gene name | lutB |
| Synonyms | yvfW |
| Essential | |
| Product | |
| Function | lactate utilization |
| MW, pI | 53 kDa, 5.848 |
| Gene length, protein length | 1437 bp, 479 aa |
| Immediate neighbours | |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
| |
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
no growth with lactate as the single carbon source PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: oxidation of lactate to pyruvate PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry:
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation: induction by lactate PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Richard Losick, Harvard Univ., Cambridge, USA homepage
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed