WalR: Difference between revisions
Appearance
No edit summary |
No edit summary |
||
| Line 30: | Line 30: | ||
<br/><br/> | <br/><br/> | ||
= [[Categories]] containing this gene/protein = | |||
{{SubtiWiki category|[[cell wall/ other]]}}, | |||
{{SubtiWiki category|[[transcription factors and their control]]}}, | |||
{{SubtiWiki category|[[essential genes]]}}, | |||
{{SubtiWiki category|[[phosphoproteins]]}} | |||
= This gene is a member of the following [[regulons]] = | |||
=The gene= | =The gene= | ||
| Line 51: | Line 60: | ||
=The protein= | =The protein= | ||
Revision as of 01:16, 9 December 2010
- Description: two-component response regulator, controls cell wall metabolism
| Gene name | walR |
| Synonyms | yycF |
| Essential | yes PubMed |
| Product | two-component response regulator |
| Function | control of cell wall metabolism |
| MW, pI | 27 kDa, 4.876 |
| Gene length, protein length | 705 bp, 235 aa |
| Immediate neighbours | walK, trnY-Phe |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context
This image was kindly provided by SubtiList
| |
Categories containing this gene/protein
cell wall/ other, transcription factors and their control, essential genes, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU40410
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: OmpR family of two-component transcription regulators
- Paralogous protein(s):
Genes controlled by WalR PubMed
- Activation by WalR: cwlO, lytE, ydjM, yocH, ftsA-ftsZ PubMed, tagA-tagB PubMed, tagD-tagE-tagF PubMed
- Repression by WalR: iseA, yjeA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylated by WalK on an Asp residue
- Cofactor(s):
- Effectors of protein activity: phosphorylation likely affects DNA-binding activity
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: P37478
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: expressed during vegetative growth, repressed during stationary phase PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
<pubmed>19019149, 18245295,18792692,</pubmed>
Original Publications
<pubmed>18573169,17350627,10094672,17827301,9829949,17581128,10878122,16030236,12950927, 19574649, 20059685 20111065 20167622 20834167 </pubmed>
