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| Biofilms are the result of the multicellular lifestyle of ''B. subtilis''. They are characterized by the formation of a matrix polysaccharide and an amyloid-like protein, [[TasA]].
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| {{CategoryTree | | {{CategoryTree |
| |Parents= | | |Parents= |
| * 4. [[Life styles]] | | * 1. [[Cellular processes]] |
| ** 4.2 [[Processes activated during stationary phase]] | | ** 1.1 [[Cell wall and cell division]] |
| |Neighbours= | | |Neighbours= |
| * 4.2.1 [[Sporulation and germination]] | | * 1.1.1 [[Easter egg|Cell wall synthesis]] |
| * 4.2.2 [[Easter egg|Biofilm formation]] | | * 1.1.2 [[Cell shape]] |
| * 4.2.3 [[Coping with stress]] | | * 1.1.3 [[Cell wall degradation/ turnover]] |
| * 4.2.4 [[Life styles -- miscellaneous]] | | * 1.1.4 [[Capsule biosynthesis and degradation]] |
| | * 1.1.5 [[Cell wall/ other]] |
| | * 1.1.6 [[Cell division]] |
| |Related= | | |Related= |
| no
| | none |
| |}} | | |}} |
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| <br/><br/><br/> | | <br/><br/><br/> |
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| ==[http://subtiwiki.uni-goettingen.de/pathways/biofilm.html Biofilm formation in ''Subti''Pathways]== | | == Subcategories == |
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| ==Labs working on biofilm formation==
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| * [[Daniel Kearns]]
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| * [[Oscar Kuipers]]
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| * [[Beth Lazazzera]]
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| * [[Richard Losick]]
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| * [[Nicola Stanley-Wall]]
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| ==Key genes and operons involved in biofilm formation==
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| * matrix polysaccharide synthesis:
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| ** ''[[epsA]]-[[epsB]]-[[epsC]]-[[epsD]]-[[epsE]]-[[epsF]]-[[epsG]]-[[epsH]]-[[epsI]]-[[epsJ]]-[[epsK]]-[[epsL]]-[[epsM]]-[[epsN]]-[[epsO]]''
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| * amyloid protein synthesis
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| ** ''[[yqxM]]-[[sipW]]-[[tasA]]''
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| * regulation
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| ** [[SlrR]]
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| ** [[SlrA]]
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| ** [[SinR]]
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| ** [[SinI]]
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| ** [[PtkA]]
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| ** [[TkmA]]
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| ** [[PtpZ]]
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| ** [[DegU]]
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| ** [[RacX]]
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| * biofilm disassembly
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| ** [[YlmE]]
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| * other proteins required for biofilm formation
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| ** [[SpeA]]
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| ** [[YmcA]]
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| ** [[YxaB]]
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| ==Key reviews==
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| <pubmed>19054118 19054118 16787201 9891794 20890834 </pubmed>
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| * additional reviews: {{PubMed|20735481}}
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