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T-box: Difference between revisions

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* Induction by threonine limitation
* Induction by threonine limitation
** ''[[thrS]], [[thrZ]]''
** ''[[thrS]], [[thrZ]]-[[ywhA]]''


* Induction by tryptophan limitation
* Induction by tryptophan limitation

Revision as of 20:14, 3 February 2010

The T-box element is an RNA switch that controls genes involved in amino acid metabolism.

In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid.

Complete list of genes controlled by T-box elements

  • Induction by alanine limitation
  • Induction by aspartate limitation
  • Induction by histidine limitation
  • Induction by phenyalanine limitation
  • Induction by serine limitation
  • Induction by tyrosine limitation

Structure of a T-box ribowsitch

<pubmed> 12547201</pubmed>


Reviews on T-box regulation

<pubmed> 19258532,7527891, 11917026 ,8348614,17381302 10546897 </pubmed>