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=Expression and regulation=
=Expression and regulation=
* '''Operon:''' ''[[tagD]]-[[tagE]]-[[tagF]]'' {{PubMed|2507871}}


* '''Operon:'''
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|7581998}}
 
* '''[[Sigma factor]]:'''  


* '''Regulation:'''  
* '''Regulation:'''  
** repressed when phosphate is available ([[PhoP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9457886 PubMed]
** repressed by phosphate ([[PhoP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9457886 PubMed]


* '''Regulatory mechanism:'''  
* '''Regulatory mechanism:'''  
** [[PhoP]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/9457886 PubMed]
** [[PhoP]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/9457886 PubMed]
** [[WalR]]: transcription activation {{PubMed|12950927}}


* '''Additional information:'''  
* '''Additional information:'''  
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=References=
=References=


<pubmed>9683503,9457886,11673441,10508782,,9457886, </pubmed>
<pubmed>9683503,9457886,11673441,10508782,2507871,12950927, 7581998</pubmed>


[[Category:Protein-coding genes]]
[[Category:Protein-coding genes]]

Revision as of 21:18, 4 January 2010

  • Description: glycerol-3-phosphate cytidylyltransferase

Gene name tagD
Synonyms
Essential yes PubMed
Product glycerol-3-phosphate cytidylyltransferase
Function biosynthesis of teichoic acid
MW, pI 15 kDa, 5.672
Gene length, protein length 387 bp, 129 aa
Immediate neighbours tagE, tagA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU35740

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: CTP + sn-glycerol 3-phosphate = diphosphate + CDP-glycerol (according to Swiss-Prot)
  • Protein family: cytidylyltransferase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure: 1N1D (complex with CDP-glycerol), 1COZ
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

<pubmed>9683503,9457886,11673441,10508782,2507871,12950927, 7581998</pubmed>