Revision as of 08:34, 13 July 2009

Description: 4-amino-5-hydroxymethyl-2-methylpyrimidine and 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate kinase

Gene name	thiD
Synonyms	yjbV
Essential	no
Product	4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate kinase
Function	biosynthesis of thiamine pyrophosphate (TPP)
MW, pI	28 kDa, 5.709
Gene length, protein length	813 bp, 271 aa
Immediate neighbours	thiF, fabI
Gene sequence (+200bp)	Protein sequence
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

Locus tag: BSU11710

Phenotypes of a mutant

Database entries

DBTBS entry: [1]

SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

Catalyzed reaction/ biological activity:

Protein family:

Paralogous protein(s): PdxK

Extended information on the protein

Kinetic information:

Domains:

Modification:

Cofactor(s):

Effectors of protein activity:

Interactions:

Localization:

Database entries

Structure:

Swiss prot entry:

KEGG entry: [3]

E.C. number:

Additional information

Expression and regulation

Operon:

Sigma factor:

Regulation:

Regulatory mechanism:

Additional information:

Biological materials

Mutant:

Expression vector:

lacZ fusion:

GFP fusion:

two-hybrid system:

Antibody:

Labs working on this gene/protein

Your additional remarks

References

@@ Line 1: / Line 1: @@
-#REDIRECT [[PdxK]]
+* '''Description:''' 4-amino-5-hydroxymethyl-2-methylpyrimidine and 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate kinase<br/><br/>
+{| align="right" border="1" cellpadding="2"
+|-
+|style="background:#ABCDEF;" align="center"|'''Gene name'''
+|''thiD''
+|-
+|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yjbV''
+|-
+|style="background:#ABCDEF;" align="center"| '''Essential''' || no
+|-
+|style="background:#ABCDEF;" align="center"| '''Product''' || 4-amino-5-hydroxymethyl-2-methylpyrimidine<br/>pyrophosphate kinase
+|-
+|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of thiamine pyrophosphate (TPP)
+|-
+|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 28 kDa, 5.709
+|-
+|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 813 bp, 271 aa
+|-
+|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[thiF]]'', ''[[fabI]]''
+|-
+|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/yjbV_nucleotide.txt     Gene sequence      (+200bp)   ]'''
+|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/yjbV_protein.txt Protein sequence]'''
+|-
+|colspan="2" | '''Genetic context''' <br/> [[Image:yjbV_context.gif]]
+ <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
+|-
+|}
+__TOC__
+<br/><br/>
+=The gene=
+=== Basic information ===
+* '''Locus tag:''' BSU11710
+===Phenotypes of a mutant ===
+=== Database entries ===
+* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/tenAI-goxB-thiSGF-yjbV.html]
+* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13151]
+=== Additional information===
+=The protein=
+=== Basic information/ Evolution ===
+* '''Catalyzed reaction/ biological activity:'''
+* '''Protein family:'''
+* '''Paralogous protein(s):''' [[PdxK]]
+=== Extended information on the protein ===
+* '''Kinetic information:'''
+* '''Domains:'''
+* '''Modification:'''
+* '''Cofactor(s):'''
+* '''Effectors of protein activity:'''
+* '''Interactions:'''
+* '''Localization:'''
+=== Database entries ===
+* '''Structure:'''
+* '''Swiss prot entry:'''
+* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU11710]
+* '''E.C. number:'''
+=== Additional information===
+=Expression and regulation=
+* '''Operon:'''
+* '''[[Sigma factor]]:'''
+* '''Regulation:'''
+* '''Regulatory mechanism:'''
+* '''Additional information:'''
+=Biological materials =
+* '''Mutant:'''
+* '''Expression vector:'''
+* '''lacZ fusion:'''
+* '''GFP fusion:'''
+* '''two-hybrid system:'''
+* '''Antibody:'''
+=Labs working on this gene/protein=
+=Your additional remarks=
+=References=
+<pubmed>14973012,, </pubmed>