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| * '''Description:''' required for normal spore cortex and coat synthesis, inhibits the proteolytic activity of [[FtsH]] (adaptor protein)<br/><br/>
| | {{#bank: SpoVM}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''spoVM''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Product''' || spore coat morphogenetic protein
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| |-
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| |style="background:#ABCDEF;" align="center"|'''Function''' || spore cortex and coat synthesis
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| |-
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15810 spoVM]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SpoVM SpoVM]
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 2 kDa, 11.026
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 78 bp, 26 aa
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| |-
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yloS]]'', ''[[rpmB]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15810 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15810 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15810 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:spoVM_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoVM_1655446_1655526_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:spoVM_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15810]]
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| |-
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/>
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|
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[sporulation proteins]]}},
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| {{SubtiWiki category|[[membrane proteins]]}}
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|
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[SigE regulon]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU15810
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| ===Phenotypes of a mutant ===
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| * reduction of sporulation efficiency due to defects in spore coat and cortex assembly {{PubMed|22463703}}
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15810&redirect=T BSU15810]
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoVM.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10776]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| ** anchors the basement layer of the spore coat to the surface of the developing spore {{PubMed|22463703}}
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| * '''Protein family:'''
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''[[Domains]]:''' contains an amphipathic alpha-helix
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| * '''Modification:'''
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| * '''[[Cofactors]]:'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| ** [[SpoIVA]]-[[SpoVM]]-[[SpoVID]] {{PubMed|19775244}}
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| ** [[SpoVM]]-[[FtsH]] {{PubMed|10913836}}
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| * '''[[Localization]]:'''
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| ** around the surface of the developing forespore {{PubMed|22463703}}
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| ** spore membrane, recognizes membrane curvature [http://www.ncbi.nlm.nih.gov/sites/entrez/19265022 PubMed]
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| ** spore coat (basement), localization depends on [[SpoIVA]] {{PubMed|22171814}}
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|
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15810&redirect=T BSU15810]
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/P37817 P37817]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU15810]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''spoVM'' {{PubMed|8231808}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoVM_1655446_1655526_1 spoVM] {{PubMed|22383849}}
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| * '''[[Sigma factor]]:''' [[SigE]] {{PubMed|8231808,15699190}}
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| * '''Regulation:'''
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| ** expressed in mother cell during sporulation ([[SigE]], [[SpoIIID]]) {{PubMed|8231808,15699190,19265022}}
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| * '''Regulatory mechanism:'''
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| == Reviews ==
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| <pubmed>23202530</pubmed>
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| == Original publications ==
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| <pubmed>10913836,18820968,8231808,9922240,19265022,12562810,9287010,17427285, 19775244 15699190 22463703 22171814 22882210 25625300</pubmed>
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| [[Category:Protein-coding genes]]
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