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* '''Description:''' replication terminator protein <br/><br/>
{{#bank: Rtp}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''rtp''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || replication terminator protein
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|style="background:#ABCDEF;" align="center"|'''Function''' || replication termination
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU18490 rtp]
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 14 kDa, 9.778 
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 366 bp, 122 aa
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[proH]]'', ''[[yoxD]]''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU18490 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU18490 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU18490 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:rtp_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rtp_2017886_2018254_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:rtp_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU18490]]
|-
|}
__TOC__
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[DNA replication]]}}
= This gene is a member of the following [[regulons]] =
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU18490
===Phenotypes of a mutant ===
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU18490&redirect=T BSU18490]
* '''DBTBS entry:''' no entry
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10738]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
** binds to nine termination sites spanning ∼430 kb of the replication terminus region {{PubMed|9642188}}
* '''Protein family:'''
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
* '''[[Localization]]:'''
** cytoplasm (according to Swiss-Prot)
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU18490&redirect=T BSU18490]
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1F4K 1F4K] (complex with DNA),  [http://www.rcsb.org/pdb/explore.do?structureId=1BM9 1BM9]
* '''UniProt:''' [http://www.uniprot.org/uniprot/P68732 P68732]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU18490]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:'''
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rtp_2017886_2018254_-1 rtp] {{PubMed|22383849}}
* '''Sigma factor:'''
* '''Regulation:'''
* '''Regulatory mechanism:'''
* '''Additional information:'''
** number of protein molecules per cell (complex medium with amino acids, without glucose): 50 {{PubMed|24696501}}
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
== Reviews ==
<pubmed> 19298368 </pubmed>
== Original publications ==
<pubmed>7746150,10209741, 19820088, 2498294 2115089 1784827 7934839 9642188 7476199 10064700 8676392 15657033 10931283 11313334 </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 11:34, 30 July 2014