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| * '''Description:''' control of the [[phosphorelay]], required for the achieving a sufficient level of [[Spo0A]]-P for sporulation initiation<br/><br/>
| | {{#bank: YaaT}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''yaaT''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Product''' || part of the [[YaaT]]-[[YmcA]]-[[YlbF]] complex
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| |-
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| |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of sporulation initiation
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00320 yaaT]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=YaaT YaaT]
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 4.838
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 825 bp, 275 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[holB]]'', ''[[yabA]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU00320 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU00320 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU00320 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:yaaT_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yaaT_41657_42484_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:yaaT_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00320]]
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| |-
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/>
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|
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[phosphorelay]]}},
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| {{SubtiWiki category|[[membrane proteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU00320
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| ===Phenotypes of a mutant ===
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| * block of sporulation at stage 0 {{PubMed|12270811}}
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| * strongly reduced [[genetic competence]], strongly reduced [[sporulation]] {{PubMed|23490197}}
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00320&redirect=T BSU00320]
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| * '''DBTBS entry:''' no entry
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10096]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:'''
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| ** [[YmcA]]-[[YlbF]]-[[YaaT]], this complex stimulates [[Spo0A]] phosphorylation in the [[phosphorelay]] {{PubMed|23490197}}
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| * '''[[Localization]]:'''
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| ** peripheral membrane, as well as to the septum, during sporulation {{PubMed|12270811}}
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00320&redirect=T BSU00320]
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/P37541 P37541]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU00320]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''[[yaaQ]]-[[yaaR]]-[[holB]]-[[yaaT]]-[[yabA]]-[[yabB]]-[[yazA]]-[[yabC]]'' {{PubMed|22383849}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yaaT_41657_42484_1 yaaT] {{PubMed|22383849}}
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| * '''Sigma factor:'''
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| * '''Regulation:'''
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| ** expressed during growth and the transition phase, expression is erduced in stationary phase {{PubMed|23490197}}
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| * '''Regulatory mechanism:'''
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| * '''Additional information:'''
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| ** number of protein molecules per cell (minimal medium with glucose and ammonium): 116 {{PubMed|24696501}}
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| ** number of protein molecules per cell (complex medium with amino acids, without glucose): 172 {{PubMed|24696501}}
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed>12270811 23490197 22383849</pubmed>
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| [[Category:Protein-coding genes]]
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