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FliD: Difference between revisions

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* '''Description:''' filament cap, serves as an extracytoplasmic chaperone required for polymerization of [[Hag|flagellin]] into the helical filament <br/><br/>
{{#bank: FliD}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''fliD''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || extracytoplasmic chaperone required for polymerization of [[Hag|flagellin]]
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || [[motility and chemotaxis]]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35340 fliD]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=FliD FliD]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 54 kDa, 4.804 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1494 bp, 498 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fliS]]'', ''[[yvyC]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35340 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35340 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35340 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:fliD_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fliD_3632911_3634407_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:fliD_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35340]]
|-
|}
__TOC__
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[motility and chemotaxis]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[SigD regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU35340
===Phenotypes of a mutant ===
* the mutation suppresses the mucoid phenotype of ''[[motA]]'' or ''[[motB]]'' mutants {{PubMed|24296669}}
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU35340&redirect=T BSU35340]
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yvyC-fliDST.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10921]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' fliD family (according to Swiss-Prot)
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''[[Domains]]:'''
* '''Modification:'''
* '''[[Cofactors]]:'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
** [[FlhA]]-[[FliD]] {{PubMed|20534509}}
** [[FliD]]-[[FliT]] {{PubMed|20534509}}
** [[FlhA]]-([[FliD]]-[[FliT]]) {{PubMed|20534509}}
* '''[[Localization]]:''' secreted (according to Swiss-Prot),  extracellular (no signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed]
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU35340&redirect=T BSU35340]
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/P39738 P39738]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU35340]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[yvyC]]-[[fliD]]-[[fliS]]-[[fliT]]'' {{PubMed|8195064}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fliD_3632911_3634407_-1 fliD] {{PubMed|22383849}}
* '''[[Sigma factor]]:''' [[SigD]] {{PubMed|8195064}}
* '''Regulation:'''
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>8195064,24296669, 20534509,18957862, </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 09:32, 17 April 2014