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GltP: Difference between revisions

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* '''Description:''' similar to H+/glutamate symporter <br/><br/>
{{#bank: GltP}}


{| align="right" border="1" cellpadding="2"
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|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''gltP''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no
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|style="background:#ABCDEF;" align="center"| '''Product''' || similar to H+/glutamate symporter
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|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02340 gltP]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=gltP gltP]'''
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 44 kDa, 8.651 
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1242 bp, 414 aa
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ybfQ]]'', ''[[gamP]]''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02340 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02340 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02340 DNA_with_flanks]
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|-
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|colspan="2" | '''Genetic context''' <br/> [[Image:gltP_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=gltP_253518_254762_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:gltP_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02340]]
|-
|}
__TOC__
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[transporters/ other]]}},
{{SubtiWiki category|[[membrane proteins]]}}
= This gene is a member of the following [[regulons]] =
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU02340
===Phenotypes of a mutant ===
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU02340&redirect=T BSU02340]
* '''DBTBS entry:''' no entry
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11015]
=== Additional information===
* A mutation was found in this gene after evolution under relaxed selection for sporulation  {{PubMed|21821766}}
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' View classification (according to Swiss-Prot)
* '''Paralogous protein(s):''' [[GltT]], [[DctP]]
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''[[Domains]]:'''
* '''Modification:'''
* '''[[Cofactors]]:'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU02340&redirect=T BSU02340]
* '''Structure:''' [http://pdb.org/pdb/explore/explore.do?structureId=4KY0 4KY0] (the glutamate transporter of ''Thermococcus kodakarensis'', 33% identity, 68% similarity) {{PubMed|24013209}}
* '''UniProt:''' [http://www.uniprot.org/uniprot/P39817 P39817]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU02340]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:'''
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=gltP_253518_254762_-1 gltP] {{PubMed|22383849}}
* '''Sigma factor:'''
* '''Regulation:'''
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>7751298, 21821766 24013209</pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 10:08, 27 October 2014