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RecR: Difference between revisions

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* '''Description:''' repair, recombination <br/><br/>
* '''Description:''' required for the formation of [[RecA]] DNA repair centers
<br/><br/>


{| align="right" border="1" cellpadding="2"  
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
|-
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|style="background:#ABCDEF;" align="center"| '''Product''' || formation of [[RecA]] DNA repair centers
|-
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || [[DNA repair/ recombination]]
|style="background:#ABCDEF;" align="center"|'''Function''' || [[DNA repair/ recombination]]
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=== Additional information===
=== Additional information===


=The protein=
=The protein=
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* '''Catalyzed reaction/ biological activity:'''  
* '''Catalyzed reaction/ biological activity:'''  
** required for the formation of [[RecA]] DNA repair centers (together with [[RecO]]) {{PubMed|24891441}}


* '''Protein family:''' recR family (according to Swiss-Prot)
* '''Protein family:''' recR family (according to Swiss-Prot)
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<pubmed> 22933559 </pubmed>
<pubmed> 22933559 </pubmed>
== Original publications ==
== Original publications ==
<pubmed>12884008,17581636, 16479537 24285298 24285298</pubmed>
<pubmed>12884008,17581636, 16479537 24285298 24285298 24891441</pubmed>


[[Category:Protein-coding genes]]
[[Category:Protein-coding genes]]

Revision as of 11:18, 4 June 2014

  • Description: required for the formation of RecA DNA repair centers


Gene name recR
Synonyms recM
Essential no
Product formation of RecA DNA repair centers
Function DNA repair/ recombination
Gene expression levels in SubtiExpress: recR
Interactions involving this protein in SubtInteract: RecR
MW, pI 21 kDa, 5.301
Gene length, protein length 594 bp, 198 aa
Immediate neighbours yaaK, yaaL
Sequences Protein DNA DNA_with_flanks
Genetic context
This image was kindly provided by SubtiList
Expression at a glance   PubMed















Categories containing this gene/protein

DNA repair/ recombination

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU00210

Phenotypes of a mutant

  • drastically reduced survival of mature dormant spores after exposure to ultrahigh vacuum desiccation and ionizing radiation that induce single strand (ss) DNA nicks and double-strand breaks (DSBs) PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • required for the formation of RecA DNA repair centers (together with RecO) PubMed
  • Protein family: recR family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

<pubmed> 22933559 </pubmed>

Original publications

<pubmed>12884008,17581636, 16479537 24285298 24285298 24891441</pubmed>