GamR

• Description: transcriptional repressor (GntR family) of the gamA-gamP operon
  
  

Gene name	gamR
Synonyms	ybgA
Essential	no
Product	transcriptional regulator (GntR family)
Function	regulation of glucosamine utilization
Gene expression levels in SubtiExpress: gamR
MW, pI	26 kDa, 5.559
Gene length, protein length	705 bp, 235 aa
Immediate neighbours	gamA, ybgB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall degradation/ turnover, utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

GamR regulon

The GamR regulon:

• gamA-gamP, gamR-ybgB

The gene

Basic information

• Locus tag: BSU02370

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: GntR family of transcription factors

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:
  • glucosamine-6-phosphate acts as molecular inducer that prevents GamR from binding to its operator sites in the promoter regions of the gamA-gamP and gamR-ybgB operons PubMed

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O31459

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: gamR-ybgB PubMed

• Expression browser: gamR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by glucosamine (GamR) PubMed

• Regulatory mechanism:
  • GamR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed> 10627040 23667565 24673833 </pubmed>