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* '''Description:''' control of cell shape and elongation <br/><br/>
{{#bank: RodA}}


{| align="right" border="1" cellpadding="2"
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|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''rodA''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ywcF, ipa-42d ''
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|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
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|style="background:#ABCDEF;" align="center"| '''Product''' || SEDS protein
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of cell shape and elongation
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38120 rodA]
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 8.759 
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1179 bp, 393 aa
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nfrA]]'', ''[[ywcE]]''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU38120 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU38120 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU38120 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:rodA_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rodA_3912332_3913513_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:rodA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38120]]
|-
|}
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[cell shape]]}},
{{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, V, W, X, Y)]]}},
{{SubtiWiki category|[[essential genes]]}},
{{SubtiWiki category|[[membrane proteins]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[SigM regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU38120
===Phenotypes of a mutant ===
essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
=== Database entries ===
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/rodA.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10588]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' ftsW/rodA/spoVE family (according to Swiss-Prot) SEDS proteins (shape, elongation, division, and sporulation)
* '''Paralogous protein(s):''' [[FtsW]], [[SpoVE]]
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''[[Domains]]:'''
* '''Modification:'''
* '''[[Cofactors]]:'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
** part of the [[elongasome]] {{PubMed|21636744,21636745}}
* '''[[Localization]]:'''
** integral membrane protein {{PubMed|21636744}}
** forms circumferentially moving patches {{PubMed|21636744}}
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/P39604 P39604]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU38120]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''rodA'' {{PubMed|9353933}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rodA_3912332_3913513_-1 rodA] {{PubMed|22383849}}
* '''Sigma factor:''' [[SigM]] [http://www.ncbi.nlm.nih.gov/sites/entrez/18179421 Pubmed]
* '''Regulation:'''
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
* [[Charles Moran]], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]
=Your additional remarks=
=References=
<pubmed>9622350,21636744,21636745,17981970,9622350, </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 15:07, 2 April 2014