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| * '''Description:''' transcription activator and repressor of [[SigG]]-dependent genes <br/><br/>
| | {{#bank: SpoVT}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''spoVT''
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yabL ''
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator
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| |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of forespore gene expression
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00560 spoVT]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=spoVT spoVT]'''
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 19 kDa, 4.676
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 534 bp, 178 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mfd]]'', ''[[yabM]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU00560 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU00560 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU00560 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:spoVT_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoVT_64099_64635_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:spoVT_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00560]]
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/><br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[transcription factors and their control]]}},
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| {{SubtiWiki category|[[sporulation proteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[SigF regulon]]}},
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| {{SubtiWiki regulon|[[SigG regulon]]}}
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| =The [[SpoVT regulon]]=
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU00560
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoVT.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10119]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:'''
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| * '''Paralogous protein(s):''' [[AbrB]], [[Abh]] (only the N-terminal domains (aa 1 through 50) are conserved between SpoVT and the two paralogues)
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| * '''[[Localization]]:''' Cytoplasm (Homogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed]
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| === Database entries ===
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| * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2W1R 2W1R] (full-length), [http://www.rcsb.org/pdb/explore.do?structureId=2W1T 2W1T] (C-terminal domain) [http://www.rcsb.org/pdb/explore.do?structureId=2RO5 2RO5] (recognition domain)
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/P37554 P37554]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU00560]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''spoVT'' [http://www.ncbi.nlm.nih.gov/sites/entrez/8755877 PubMed]
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoVT_64099_64635_1 spoVT] {{PubMed|22383849}}
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| * '''Sigma factor:''' [[SigF]] {{PubMed|15699190}}, [[SigG]] {{PubMed|15699190,8755877}}
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| * '''Regulation:''' expressed in the forespore ([[SigG]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8755877 PubMed]
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| * '''Regulatory mechanism:'''
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed>16497325,18996130,15063493,8755877 , 16479537, 16159768 22522895</pubmed>
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| [[Category:Protein-coding genes]]
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