Pta: Difference between revisions
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=== Database entries === | === Database entries === | ||
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU37660&redirect=T BSU37660] | |||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/pta.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/pta.html] | ||
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=== Database entries === | === Database entries === | ||
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU37660&redirect=T BSU37660] | |||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1XCO 1XCO] (complex with acetylphosphate), [http://www.rcsb.org/pdb/explore.do?structureId=1TD9 1TD9] | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1XCO 1XCO] (complex with acetylphosphate), [http://www.rcsb.org/pdb/explore.do?structureId=1TD9 1TD9] | ||
Revision as of 15:05, 2 April 2014
- Description: phosphotransacetylase
| Gene name | pta |
| Synonyms | ipa-88d, ywfJ |
| Essential | no |
| Product | phosphotransacetylase |
| Function | overflow metabolism |
| Gene expression levels in SubtiExpress: pta | |
| Metabolic function and regulation of this protein in SubtiPathways: pta | |
| MW, pI | 34 kDa, 4.649 |
| Gene length, protein length | 969 bp, 323 aa |
| Immediate neighbours | cysL, ywfI |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Categories containing this gene/protein
carbon core metabolism, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU37660
Phenotypes of a mutant
Database entries
- BsubCyc: BSU37660
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Acetyl-CoA + phosphate = CoA + acetyl phosphate (according to Swiss-Prot)
- Protein family: phosphate acetyltransferase and butyryltransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation on (Ser-123 OR Thr-128 OR Ser-129) PubMed
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- BsubCyc: BSU37660
- UniProt: P39646
- KEGG entry: [3]
- E.C. number: 2.3.1.8
Additional information
Expression and regulation
- Operon: pta PubMed
- Regulation:
- expression activated by glucose (2.6 fold) (CcpA) PubMed
- Additional information:
Biological materials
- Mutant: GP668 (aphA3), available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
<pubmed> 15755952</pubmed>
Original publications
Additional publications: PubMed <pubmed>10559153, 12850135 17218307 10559153 10423526, 16283428 23054816</pubmed>