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PheS: Difference between revisions

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= [[Categories]] containing this gene/protein =
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[translation]]}},
{{SubtiWiki category|[[translation]]}},
{{SubtiWiki category|[[essential genes]]}},
{{SubtiWiki category|[[essential genes]]}},
{{SubtiWiki category|[[universally conserved proteins]]}}
{{SubtiWiki category|[[universally conserved proteins]]}},
[[most abundant proteins]]


= This gene is a member of the following [[regulons]] =
= This gene is a member of the following [[regulons]] =
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=== Additional information===
=== Additional information===


=The protein=
=The protein=
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* '''Kinetic information:'''
* '''Kinetic information:'''


* '''Domains:'''  
* '''[[Domains]]:'''  


* '''Modification:'''
* '''Modification:'''


* '''Cofactor(s):'''
* '''[[Cofactors]]:'''


* '''Effectors of protein activity:'''
* '''Effectors of protein activity:'''
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pheS_2929438_2930472_-1 pheS] {{PubMed|22383849}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pheS_2929438_2930472_-1 pheS] {{PubMed|22383849}}


* '''Sigma factor:''' [[SigA]] {{PubMed|2127701}}
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|2127701}}


* '''Regulation:'''  
* '''Regulation:'''  
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* '''Additional information:'''
* '''Additional information:'''
** belongs to the 100 [[most abundant proteins]] {{PubMed|15378759}}


=Biological materials =
=Biological materials =
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=References=
=References=


<pubmed>19258532,2127701 , </pubmed>
<pubmed>19258532,2127701 , 15378759</pubmed>


[[Category:Protein-coding genes]]
[[Category:Protein-coding genes]]

Revision as of 16:23, 5 March 2014

Gene name pheS
Synonyms
Essential yes PubMed
Product phenylalanyl-tRNA synthetase (alpha subunit)
Function translation
Gene expression levels in SubtiExpress: pheS
Interactions involving this protein in SubtInteract: PheS
Metabolic function and regulation of this protein in SubtiPathways:
pheS
MW, pI 38 kDa, 5.083
Gene length, protein length 1032 bp, 344 aa
Immediate neighbours pheT, ysgA
Sequences Protein DNA DNA_with_flanks
Genetic context
This image was kindly provided by SubtiList
Expression at a glance   PubMed















Categories containing this gene/protein

translation, essential genes, universally conserved proteins, most abundant proteins

This gene is a member of the following regulons

T-box

The gene

Basic information

  • Locus tag: BSU28640

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe) (according to Swiss-Prot)
  • Protein family: Phe-tRNA synthetase alpha chain type 1 subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure: 1PYS (from Thermus thermophilus hb8 mutant, 37% identity, 56% similarity) PubMed
  • KEGG entry: [3]

Additional information

universally conserved protein

Expression and regulation

  • Regulation:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

<pubmed>19258532,2127701 , 15378759</pubmed>