CitS

• Description: two-component sensor kinase, regulation of citrate uptake
  
  

Gene name	citS
Synonyms	yflR
Essential	no
Product	two-component sensor kinase
Function	regulation of citrate uptake
Gene expression levels in SubtiExpress: citS
Interactions involving this protein in SubtInteract: CitS
Metabolic function and regulation of this protein in SubtiPathways: citS
MW, pI	59 kDa, 6.481
Gene length, protein length	1626 bp, 542 aa
Immediate neighbours	yflS, citT
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources, protein modification, transcription factors and their control, membrane proteins, phosphoproteins

The gene

Basic information

• Locus tag: BSU07580

Phenotypes of a mutant

no growth with citrate as sole carbon source PubMed

Database entries

• BsubCyc: BSU07580

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of CitT

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain

• Modification: autophosphorylation on a His residue

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • CitS-CitT

• Localization:
  • cell membrane (Heterogeneous) PubMed

Database entries

• BsubCyc: BSU07580

• Structure:

• UniProt: O34427

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: citS-citT-yflP PubMed

• Expression browser: citS PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed>10094672,16842348,10972810,,16479537 </pubmed>