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| * '''Description:''' [[ABC transporter]] for guanosine (membrane protein) <br/><br/>
| | {{#bank: NupP}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''nupP''
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yufP ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || [[ABC transporter]] for guanosine
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| |-
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| |style="background:#ABCDEF;" align="center"|'''Function''' || uptake of guanosine
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31560 nupP]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=NupP NupP]
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 36 kDa, 9.389
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1044 bp, 348 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nupO]]'', ''[[nupQ]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU31560 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU31560 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU31560 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:yufP_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yufP_3242610_3243656_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:nupP_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31560]]
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[ABC transporters]]}},
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| {{SubtiWiki category|[[biosynthesis/ acquisition of nucleotides]]}},
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| {{SubtiWiki category|[[membrane proteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[CodY regulon]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU31560
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''DBTBS entry:''' no entry
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12351]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:''' AraH/rbsC subfamily (according to Swiss-Prot)
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| ** [[NupO]]-([[NupP]]-[[NupQ]]) {{PubMed|10092453}}
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| * '''[[Localization]]:''' cell membrane {{PubMed|10092453}}
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| === Database entries ===
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/O05254 O05254]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU31560]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''[[nupN]]-[[nupO]]-[[nupP]]-[[nupQ]]'' {{PubMed|21926227}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yufP_3242610_3243656_1 nupP] {{PubMed|22383849}}
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| * '''Sigma factor:''' [[SigA]] {{PubMed|21926227}}
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| * '''Regulation:'''
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| ** repressed during growth in the presence of branched chain amino acids ([[CodY]]) {{PubMed|12618455,21699902,21926227}}
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| * '''Regulatory mechanism:'''
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| ** [[CodY]]: transcription repression {{PubMed|12618455,21699902,21926227}}
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed>10092453,21926227,12618455, </pubmed>
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| [[Category:Protein-coding genes]]
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