CotF

• Description: spore coat protein
  
  

Gene name	cotF
Synonyms
Essential	no
Product	spore coat protein
Function	resistance of the spore
Gene expression levels in SubtiExpress: cotF
MW, pI	18 kDa, 7.374
Gene length, protein length	480 bp, 160 aa
Immediate neighbours	yyzH, hypR
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

• Locus tag: BSU40530

Database entries

• BsubCyc: BSU40530

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: cotF family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • inner spore coat PubMed

Database entries

• BsubCyc: BSU40530

• Structure:

• UniProt: P23261

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cotF (according to DBTBS)

• Expression browser: cotF PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK, SpoIIID) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:
  • 1S106 ( cotF::cat), PubMed, available at BGSC
  • 1S107 ( cotF::cat), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed>1708381, 19933362, 15699190,15383836</pubmed>