GerBC

• Description: lipoprotein, nutrient receptor, germination response to the combination of glucose, fructose, and KCl
  
  

Gene name	gerBC
Synonyms
Essential	no
Product	nutrient receptor
Function	germination
Gene expression levels in SubtiExpress: gerBC
Interactions involving this protein in SubtInteract: GerBC
MW, pI	42 kDa, 9.06
Gene length, protein length	1122 bp, 374 aa
Immediate neighbours	gerBB, ywtG
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

germination, membrane proteins

This gene is a member of the following regulons

SigG regulon

The gene

Basic information

• Locus tag: BSU35820

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: gerABKC lipoprotein family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:
  • has an N-terminal signal sequence, lipidated on a Cys residue adjacent to the signal peptide PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • GerBA-GerBB-GerBC (tentative receptor complex) PubMed
  • GerBC is part of the germinosome in the spore inner membrane PubMed

• Localization:
  • outer surface of the inner spore membrane PubMed

Database entries

• Structure: 3N54 PubMed

• UniProt: P39571

• KEGG entry: [3]

• E.C. number:

Additional information

• 700 molecules are present per spore PubMed

Expression and regulation

• Operon: gerBA-gerBB-gerBC PubMed

• Expression browser: gerBC PubMed

• Sigma factor: SigG PubMed

• Regulation:
  • expressed late during sporulation in the forespore (SigG) PubMed

• Regulatory mechanism:

• Additional information:
  • 700 molecules are present per spore PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed>7812448,12670969,15774895,15699190,8012571,16352818, 20654628 21685283 21696470 22493018 23335419 23396907 16740944 23749970</pubmed>