SbcD

• Description: exonuclease SbcD homolog
  
  

Gene name	sbcD
Synonyms	yixA
Essential	no
Product	exonuclease SbcD homolog
Function	unknown
Gene expression levels in SubtiExpress: sbcD
MW, pI	43 kDa, 5.003
Gene length, protein length	1173 bp, 391 aa
Immediate neighbours	addA, sbcC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

DNA repair/ recombination, genetic competence

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

• Locus tag: BSU10640

Database entries

• BsubCyc: BSU10640

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: sbcD family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: Cytoplasm (Homogeneous) PubMed

Database entries

• BsubCyc: BSU10640

• Structure:

• UniProt: P23479

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: addB-addA-sbcD-sbcC-hlpB PubMed

• Expression browser: sbcD PubMed

• Sigma factor:

• Regulation:
  • positive regulation by ComK PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • GP894 (sbcCD::kan), available in Stülke lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed>8493111,11948146 22383849, 16479537</pubmed>