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* '''Description''': D-alanine aminotransferase<br/><br/> | |||
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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=== Additional information=== | === Additional information=== | ||
* Another gene coding for O6-methylguanine DNA alkyltransferase was formely known as dat, it is now called [[ogt]] | |||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dat_1041994_1042842_1 dat] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dat_1041994_1042842_1 dat] {{PubMed|22383849}} | ||
* '''Sigma factor:''' | * '''[[Sigma factor]]:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
Revision as of 11:33, 5 June 2013
- Description: D-alanine aminotransferase
| Gene name | dat |
| Synonyms | yheM |
| Essential | no |
| Product | D-alanine aminotransferase |
| Function | peptidoglycan precursor biosynthesis |
| Gene expression levels in SubtiExpress: dat | |
| Metabolic function and regulation of this protein in SubtiPathways: Cell wall | |
| MW, pI | 31 kDa, 4.871 |
| Gene length, protein length | 846 bp, 282 aa |
| Immediate neighbours | yheN, nhaC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Categories containing this gene/protein
cell wall synthesis, biosynthesis of cell wall components
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU09670
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
- Another gene coding for O6-methylguanine DNA alkyltransferase was formely known as dat, it is now called ogt
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate (according to Swiss-Prot)
- Protein family: class-IV pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1G2W (E177S Mutant, Geobacillus stearothermophilus, 43% identity)
- UniProt: O07597
- KEGG entry: [2]
- E.C. number: 2.6.1.21
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
<pubmed>9003455,17183219 </pubmed>