Revision as of 12:06, 13 May 2013

Description: lactate permease, excretion

Gene name	lctP
Synonyms	ycgC
Essential	no
Product	L-lactate permease
Function	lactate excretion
*Gene expression levels in SubtiExpress*: lctP
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism
MW, pI	57 kDa, 9.766
Gene length, protein length	1623 bp, 541 aa
Immediate neighbours	ldh, mdr
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance PubMed

Categories containing this gene/protein

transporters/ other, carbon core metabolism, membrane proteins

This gene is a member of the following regulons

Rex regulon

The gene

Basic information

Locus tag: BSU03060

Phenotypes of a mutant

Database entries

DBTBS entry: no entry

SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

Catalyzed reaction/ biological activity:

Protein family: lactate permease family (according to Swiss-Prot)

Paralogous protein(s): LutP

Extended information on the protein

Kinetic information:

Domains:

Modification:

Cofactor(s):

Effectors of protein activity:

Interactions:

Localization:
- cell membrane (according to Swiss-Prot)

Database entries

Structure:

UniProt: P55910

KEGG entry: [2]

E.C. number:

Additional information

Expression and regulation

Operon: ldh-lctP PubMed

Expression browser: lctP PubMed

Sigma factor: SigA PubMed

Regulation:
- induced under anaerobic conditions (Rex) PubMed

Regulatory mechanism:
- Rex: transcription repression PubMed

Additional information:

Biological materials

Mutant:

Expression vector:

lacZ fusion:

GFP fusion:

two-hybrid system:

Antibody:

Labs working on this gene/protein

Your additional remarks

References

@@ Line 14: / Line 14: @@
 |style="background:#ABCDEF;" align="center"|'''Function''' || lactate excretion
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU03060 lctP]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03060 lctP]
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]'''
@@ Line 24: / Line 24: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ldh]]'', ''[[mdr]]''
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12100&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU03060 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU03060 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU03060 Advanced_DNA]
 |-
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