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RNA polymerase: Difference between revisions

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* [[NusA]]: essential elongation factor
* [[NusA]]: essential elongation factor
* [[GreA]]: resolve promoter proximal pausing of RNA polymerase {{PubMed|21515770}}
* [[GreA]]: resolve promoter proximal pausing of RNA polymerase {{PubMed|21515770}}
* [[CshA]]: [[DEAD-box RNA helicase]] {{PubMed|21710567}}
* [[CshA]]: [[DEAD-box RNA helicases|DEAD-box RNA helicase]] {{PubMed|21710567}}


===Temporary interaction partners===
===Temporary interaction partners===

Revision as of 08:50, 2 July 2011

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The enzyme responsible for transcription

Components of the RNA polymerase

Core subunits

Sigma factors

  • In addition to the housekeeping sigma factor, SigA, there are several other sigma factors with different promoter recognition specifiity that are active under specific conditions (such as stress or sporulation)

Small accessory subunits

  • RpoE: delta subunit
  • YkzG: epsilon subunit
  • YloH: omega subunit

Other interaction partners

Temporary interaction partners

  • Spx: transcription regulator, interacts with RpoA
  • MgsR: transcription regulator orthologous to Spx, interacts with RpoA

Back to protein-protein interactions

References

Reviews

<pubmed> 18599813 7708009 18410247 19889534 19489723 18280161 21233849 </pubmed>

The structure of RNA polymerase

<pubmed> 12732296 12581657 11297923 19735077 </pubmed>

Important original publications: PubMed

<pubmed> 21350489 21515770 </pubmed>