Jump to content

Easter egg: Difference between revisions

From SubtiWiki
← Older editNewer edit →
Lflorez (talk | contribs)
31,300 edits
No edit summary
Lflorez (talk | contribs)
31,300 edits
No edit summary
Line 1: Line 1:
* '''Description:''' RNA component of [[RNase]] P <br/><br/>
* '''Description:''' 6S RNA<br/><br/>


{| align="right" border="1" cellpadding="2"  
{| align="right" border="1" cellpadding="2"  
|-
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''rnpB''
|''bsrB''
|-
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''rnaP ''
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
|-
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || RNA component of ribonuclease P <br/>([[RNase]] P) (catalytic subunit, ribozyme)
|style="background:#ABCDEF;" align="center"| '''Product''' || 6S RNA
|-
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || cleavage of precursor sequences <br/>from the 5' ends of pre-tRNAs
|style="background:#ABCDEF;" align="center"|'''Function''' || antagonist of [[SigA]]
|-
|-
|style="background:#ABCDEF;" align="center"| '''Gene length''' ||  401 bp
|style="background:#ABCDEF;" align="center"| '''Gene length''' ||  203 bp
|-
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ypsC]]'', ''[[ypsB]]''
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yocI]]'', ''[[azoR1]]''
|-
|-
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/rnpB_nucleotide.txt    Gene sequence      (+200bp)  ]'''  
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE.txt    Gene sequence      (+200bp)  ]'''  
 
|-
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:rnpB_context.gif]]
|colspan="2" | '''Genetic context''' <br/> [[Image:BsrB_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|-
|}
|}
Line 28: Line 26:
__TOC__
__TOC__


<br/><br/><br/><br/><br/><br/><br/>
<br/><br/>


<br/><br/><br/><br/><br/>
= [[Categories]] containing this gene/protein =
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[Rnases]]}},
{{SubtiWiki category|[[sigma factors and their control]]}},
{{SubtiWiki category|[[translation]]}},
{{SubtiWiki category|[[ncRNA]]}}
{{SubtiWiki category|[[ncRNA]]}}


Line 48: Line 46:
=== Database entries ===
=== Database entries ===


* '''DBTBS entry:''' no entry
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/bsrB.html]
 
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG00045]
 
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2A64 2A64] (from Geobacillus stearothermophilus),  [http://www.rcsb.org/pdb/explore.do?structureId=1NBS 1NBS] (specificity domain)


* '''SubtiList entry:''' no entry
* '''Structure:'''


=== Additional information===


=The RNA=


* '''Biological activity:''' 5' end maturation of precursor tRNAs


* '''RNA family:'''
* '''cofactor:''' divalent cations (Ca(II) or Mg (II)) for the stabilization of the complex with pre-tRNA {{PubMed|20434461}}
* '''interaction:''' [[RnpA]]-RnpB
=== Additional information===


=Expression and regulation=
=Expression and regulation=


* '''Operon:'''  
* '''Operon:''' ''bsrB'' [http://www.ncbi.nlm.nih.gov/sites/entrez/11886746 PubMed]


* '''Sigma factor:'''  
* '''Sigma factor:'''  


* '''Regulation:'''  
* '''Regulation:''' expressed during vegetative growth[http://www.ncbi.nlm.nih.gov/sites/entrez/11886746 PubMed]


* '''Regulatory mechanism:'''  
* '''Regulatory mechanism:'''  
Line 88: Line 77:
* '''lacZ fusion:'''
* '''lacZ fusion:'''


* '''GFP fusion:'''


* '''two-hybrid system:'''
=Labs working on this gene/RNA=


* '''Antibody:'''
* Kouji Nakamura, Tsukuba, University, Japan
 
* [[Roland Hartmann]], Philipps-Universität Marburg, Marburg, Germany, [http://www.uni-marburg.de/fb16/ipc/ag_hartmann homepage]
=Labs working on this gene/RNA=
* [[Carol Fierke]], University of Michigan, Ann Arbor, USA [https://www.chem.lsa.umich.edu/chem/faculty/facultyDetail.php?Uniqname=fierke homepage]
* [[Roland Hartmann]], Marburg University, Germany [http://www.pharmazie.uni-marburg.de/pharmchem/akhartmann/ag_hartmann.htm homepage]


=Your additional remarks=
=Your additional remarks=


=References=
=References=
==Reviews==
<pubmed> 19215776 17868095 14691942 16650980 16980936 16679018 14550630 </pubmed>


==Original Publications==
<pubmed>15811922,,11886746 15811922, </pubmed>
<pubmed>16470227,17355991,11812129,10390342,11454206, 19549719,11454206, 19717440 ,20133747  19932118 20188108 20434461 17299131 14510496 12951523 12836338 11577704 20557101 </pubmed>


[[Category:small RNA]]
[[Category:small RNA]]

Revision as of 13:50, 8 December 2010

  • Description: 6S RNA

Gene name bsrB
Synonyms
Essential no
Product 6S RNA
Function antagonist of SigA
Gene length 203 bp
Immediate neighbours yocI, azoR1
Gene sequence (+200bp)
Genetic context








Categories containing this gene/protein

sigma factors and their control, ncRNA

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: no entry
  • Structure:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: expressed during vegetative growthPubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:


Labs working on this gene/RNA

  • Kouji Nakamura, Tsukuba, University, Japan
  • Roland Hartmann, Philipps-Universität Marburg, Marburg, Germany, homepage

Your additional remarks

References

<pubmed>15811922,,11886746 15811922, </pubmed>

Retrieved from "https://subtiwiki.uni-goettingen.de/wiki/index.php?title=Easter_egg&oldid=134285"