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* '''Description:''' elemental iron uptake system (binding protein) <br/><br/>
{{#bank: EfeB}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''ywbN''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ipa-29d ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || elemental iron uptake system (binding protein)
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || iron uptake
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 8.64 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1248 bp, 416 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywbO]]'', ''[[ywbM]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15852&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:ywbN_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|}
__TOC__
<br/><br/>
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU38260
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ywbLMN.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10575]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' DyP-type peroxidase family (according to Swiss-Prot)
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''Interactions:'''
* '''Localization:''' secreted (according to Swiss-Prot),  extracellular, secreted by the [[TatAY]]-[[TatCY]] complex
=== Database entries ===
* '''Structure:'''
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P39597 P39597]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU38260]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:'''
* '''[[Sigma factor]]:'''
* '''Regulation:'''
** repressed unless the cells enter an iron starvation ([[Fur]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]
* '''Regulatory mechanism:'''
** [[Fur]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
[[Jan Maarten van Dijl]], Groningen, Netherlands
=Your additional remarks=
=References=
<pubmed> 19383693 </pubmed>

Latest revision as of 17:16, 5 August 2015