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* '''Description:''' fructose-1-phosphate kinase <br/><br/>
{{#bank: FruK}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''fruK''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''fruB ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || fructose-1-phosphate kinase
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || fructose utilization
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 4.885 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 909 bp, 303 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fruR]]'', ''[[fruA]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13312&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:fruK_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|}
__TOC__
<br/><br/>
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU14390
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/fruRKA.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12588]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:''' ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate (according to Swiss-Prot)
* '''Protein family:''' carbohydrate kinase pfkB family (according to Swiss-Prot)
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''Interactions:'''
* '''Localization:'''
=== Database entries ===
* '''Structure:'''
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O31714 O31714]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU14390]
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.1.56 2.7.1.56]
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[fruR]]-[[fruK]]-[[fruA]]''
* '''[[Sigma factor]]:'''
* '''Regulation:'''
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>10627040, </pubmed>
# Reizer et al. (1999) Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of ''Bacillus subtilis''. ''Microbiology'' '''145:''' 3419-3429 [http://www.ncbi.nlm.nih.gov/pubmed/10627040 PubMed]
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]

Latest revision as of 10:08, 17 April 2014