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* '''Description:''' co-[[sigma factor]] (with [[YvrI]]) <br/><br/>
{{#bank: YvrHa}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yvrHa''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' rsoA''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || write here
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || co-[[sigma factor]] (with [[YvrI]])
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || RNA polymerase [[sigma factor]]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9.5 kDa, 4.69
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 240 bp, 79 amino acids
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yvrI]]'', ''[[yvrHb]]''
|-
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_nucleotide.txt    Gene sequence      (+200bp)  ]'''
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_protein.txt Protein sequence]'''
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:YvrHa_yvrHb_context.GIF]]
|-
|}
__TOC__
<br/><br/>
=The gene=
=== Basic information ===
* '''Locus tag:'''
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' no entry
* '''SubtiList entry:''' does not exist
=== Additional information===
The sequence of the former ''yvrH'' gene was corrected, and does now contain two genes, ''[[yvrHa]]'' and ''[[yvrHb]]''.
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:'''
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''Interactions:''' [[YvrI]]-[[YvrHa]],  [[YvrI]]-[[YvrHa]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19047353 PubMed]
* '''Localization:'''
=== Database entries ===
* '''Structure:'''
* '''Swiss prot entry:'''
* '''KEGG entry:''' no entry
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[yvrI]]-[[yvrHa]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/19047353 PubMed]
* '''[[Sigma factor]]:''' [[YvrI]]-[[YvrHa]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19047353 PubMed]
* '''Regulation:''' induced by acidic growth conditions [http://www.ncbi.nlm.nih.gov/sites/entrez/19047353 PubMed]
* '''Regulatory mechanism:''' activated by [[YvrHb]]  [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed]
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
[[John Helmann]], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]
=Your additional remarks=
=References=
<pubmed>19047353, </pubmed>
# MacLellan et al. (2009) The YvrI alternative sigma factor is essential for acid stress induction of oxalate decarboxylase in ''Bacillus subtilis''. ''J. Bacteriol.'' '''191:''' 931-939. [http://www.ncbi.nlm.nih.gov/sites/entrez/19047353 PubMed]
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]

Latest revision as of 14:44, 2 April 2014