Latest revision as of 12:06, 28 January 2017

Description: regulatory RNA, ncRNA, antisense for txpA

Gene name	ratA
Synonyms
Essential	no
Product	txpA antisense RNA
Function	control of txpA expression
Gene length	222 bp
Immediate neighbours	txpA, bsrH
Gene sequence (+200bp)
Genetic context File:GenE context.gif
Expression at a glance PubMed

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, Skin element, ncRNA

This gene is a member of the following regulons

The ratA regulon: txpA

The gene

Basic information

Locus tag:

Phenotypes of a mutant

Database entries

BsubCyc: ?
BsubCyc: ?

DBTBS entry: no entry

SubtiList entry:

Structure:

Additional information

The RNA

binds the txpA mRNA and triggers its degradation PubMed

Expression and regulation

Operon:

Sigma factor:

Regulation:

Regulatory mechanism:

Additional information:
- the txpA mRNA-RatA RNA duplex is degraded by RNase III PubMed

Biological materials

Mutant:

Expression vector:

lacZ fusion:

GFP fusion:

two-hybrid system:

Antibody:

Labs working on this gene/protein

Richard Losick, Harvard University, Cambridge, USA Homepage

Your additional remarks

References

Reviews

Original publications

@@ Line 1: / Line 1: @@
-* '''Description:''' write here <br/><br/>
+* '''Description:''' regulatory RNA,  [[small RNAs|ncRNA]], antisense for ''[[txpA]]'' <br/><br/>
 {| align="right" border="1" cellpadding="2"
 |-
 |style="background:#ABCDEF;" align="center"|'''Gene name'''
-|''genE''
+|''ratA''
 |-
 |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
 |-
-|style="background:#ABCDEF;" align="center"| '''Essential''' || write here
+|style="background:#ABCDEF;" align="center"| '''Essential''' || no
 |-
-|style="background:#ABCDEF;" align="center"| '''Product''' || write here
+|style="background:#ABCDEF;" align="center"| '''Product''' || ''[[txpA]]'' [[small RNAs|antisense RNA]]
 |-
-|style="background:#ABCDEF;" align="center"|'''Function''' || write here
+|style="background:#ABCDEF;" align="center"|'''Function''' || control of ''[[txpA]]'' expression
 |-
-|style="background:#ABCDEF;" align="center"| '''MW, pI''' || xx,x kDa, y.yy
+|style="background:#ABCDEF;" align="center"| '''Gene length''' || 222 bp
 |-
-|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || aaa bp, bbb amino acids
+|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[txpA]]'', ''[[bsrH]]''
-|-
-|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[genA]]'', ''[[genB]]''
 |-
 |style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_nucleotide.txt     Gene sequence      (+200bp)   ]'''
-|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_protein.txt Protein sequence]'''
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:genE_context.gif]]
+|-
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=S976_2678362_2678577_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ratA_expression.png|500px]]
 |-
 |}
@@ Line 31: / Line 30: @@
 <br/><br/>
+= [[Categories]] containing this gene/protein =
+{{SubtiWiki category|[[toxins, antitoxins and immunity against toxins]]}},
+{{SubtiWiki category|[[Skin element]]}},
+{{SubtiWiki category|[[ncRNA]]}}
+= This gene is a member of the following [[regulons]] =
+=The [[ratA regulon]]: ''[[txpA]]'' =
 =The gene=
 === Basic information ===
-* '''Coordinates (CDS):'''
+* '''Locus tag:'''
 ===Phenotypes of a mutant ===
 === Database entries ===
+* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]
+* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]
-* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/rocG.html]
+* '''DBTBS entry:''' no entry
 * '''SubtiList entry:'''
-=== Additional information===
-=The protein=
-=== Basic information/ Evolution ===
-* '''Catalyzed reaction/ biological activity:'''
-* '''Protein family:'''
-* '''Paralogous protein(s):'''
-=== Extended information on the protein ===
-* '''Kinetic information:'''
-* '''Domains:'''
-* '''Modification:'''
-* '''Cofactor(s):'''
-* '''Effectors of protein activity:'''
-* '''Interactions:'''
-* '''Localization:'''
-=== Database entries ===
 * '''Structure:'''
-* '''Swiss prot entry:'''
+=== Additional information===
-* '''KEGG entry:'''
-* '''E.C. number:'''
+=The RNA=
-=== Additional information===
+binds  the ''[[txpA]]'' mRNA and triggers its degradation [http://www.ncbi.nlm.nih.gov/sites/entrez/16166525 PubMed]
 =Expression and regulation=
@@ Line 90: / Line 66: @@
 * '''Operon:'''
-* '''Sigma factor:'''
+* '''[[Sigma factor]]:'''
 * '''Regulation:'''
@@ Line 96: / Line 72: @@
 * '''Regulatory mechanism:'''
 * '''Additional information:'''
+** the ''[[txpA]]'' mRNA-''[[RatA]]'' RNA duplex is degraded by [[rnc|RNase III]] {{PubMed|23300471}}
 =Biological materials =
@@ Line 113: / Line 90: @@
 =Labs working on this gene/protein=
+[[Richard Losick]], Harvard University, Cambridge, USA [http://www.mcb.harvard.edu/Losick/ Homepage]
 =Your additional remarks=
 =References=
+==Reviews==
+<pubmed> 23300472 </pubmed>
+==Original publications==
+<pubmed>16166525, 23300471</pubmed>
-# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
+[[Category:small RNA]]