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* '''Description:''' write here <br/><br/>
{{#bank: pdaC}}
 
* '''Description:''' peptidoglycan deacetylase C <br/><br/>


{| align="right" border="1" cellpadding="2"  
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
|-
|-
|style="background:#ABCDEF;" align="center"| '''Product''' ||  
|style="background:#ABCDEF;" align="center"| '''Product''' || polysaccharide deacetylase C
|-
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|style="background:#ABCDEF;" align="center"|'''Function''' || cell wall modification
|-
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 53 kDa, 9.105   
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 53 kDa, 9.105   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cotT]]'', ''[[yjfA]]''
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cotT]]'', ''[[yjfA]]''
|-
|-
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/yjeA_nucleotide.txt    Gene sequence     (+200bp)  ]'''
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU12100 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU12100 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU12100 DNA_with_flanks]
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/yjeA_protein.txt Protein sequence]'''
|-
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:yjeA_context.gif]]
|colspan="2" | '''Genetic context''' <br/> [[Image:yjeA_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|-
|}
|}
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<br/><br/>
<br/><br/>
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[cell wall/ other]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[WalR regulon]]}}


=The gene=
=The gene=
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=== Basic information ===
=== Basic information ===


* '''Coordinates:'''
* '''Locus tag:''' BSU12100


===Phenotypes of a mutant ===
===Phenotypes of a mutant ===
* sensitive to lysozyme treatment  {{PubMed|22277649}}


=== Database entries ===
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU12100&redirect=T BSU12100]


* '''DBTBS entry:''' no entry
* '''DBTBS entry:''' no entry
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* '''Catalyzed reaction/ biological activity:'''  
* '''Catalyzed reaction/ biological activity:'''  
** deacetylates N-acetylmuramic acid (MurNAc) but not GlcNAc from peptidoglycan {{PubMed|22277649}}


* '''Protein family:'''
* '''Protein family:''' polysaccharide deacetylase family (according to Swiss-Prot)


* '''Paralogous protein(s):'''
* '''Paralogous protein(s):'''
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* '''Kinetic information:'''
* '''Kinetic information:'''
 
** K(m)=4.8 mM and k(cat)=0.32 s(-1) (toward ''B. subtilis'' peptidoglycan) {{PubMed|22277649}}
* '''Domains:'''  
* '''Domains:'''  


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=== Database entries ===
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU12100&redirect=T BSU12100]


* '''Structure:'''
* '''Structure:'''


* '''Swiss prot entry:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/O34798 O34798]


* '''KEGG entry:'''
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU12100]


* '''E.C. number:'''
* '''E.C. number:'''
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* '''Operon:'''  
* '''Operon:'''  


* '''Sigma factor:'''  
* '''[[Sigma factor]]:'''  


* '''Regulation:'''  
* '''Regulation:''' repessed by [[WalR]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17581128 PubMed]


* '''Regulatory mechanism:'''  
* '''Regulatory mechanism:'''  


* '''Additional information:'''  
* '''Additional information:'''


=Biological materials =
=Biological materials =
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=References=
=References=


# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
<pubmed>17878218,17581128, 22277649 23199363</pubmed>
 
[[Category:Protein-coding genes]]

Latest revision as of 10:25, 2 January 2017

pdaC

  • Description: peptidoglycan deacetylase C

Gene name yjeA
Synonyms
Essential no
Product polysaccharide deacetylase C
Function cell wall modification
MW, pI 53 kDa, 9.105
Gene length, protein length 1401 bp, 467 aa
Immediate neighbours cotT, yjfA
Sequences Protein DNA DNA_with_flanks
Genetic context
This image was kindly provided by SubtiList



Categories containing this gene/protein

cell wall/ other

This gene is a member of the following regulons

WalR regulon

The gene

Basic information

  • Locus tag: BSU12100

Phenotypes of a mutant

  • sensitive to lysozyme treatment PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • deacetylates N-acetylmuramic acid (MurNAc) but not GlcNAc from peptidoglycan PubMed
  • Protein family: polysaccharide deacetylase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
    • K(m)=4.8 mM and k(cat)=0.32 s(-1) (toward B. subtilis peptidoglycan) PubMed
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

<pubmed>17878218,17581128, 22277649 23199363</pubmed>

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