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| * '''Description:''' transcriptional activator (AraC family) of the rhamnogalacturonan operon <br/><br/>
| | {{#bank: RhgR}} |
| {| align="right" border="1" cellpadding="2" | |
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''yesS''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional activator of the rhamnogalacturonan operon
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| |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of pectin utilization
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07010 yesS]
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=YesS YesS]
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 87 kDa, 7.77
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 2283 bp, 761 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yesR]]'', ''[[yesT]]''
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| |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU07010 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU07010 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU07010 DNA_with_flanks]
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| |colspan="2" | '''Genetic context''' <br/> [[Image:yesS_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yesS_765838_768123_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:yesS_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07010]]
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| |-
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/>
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|
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[utilization of specific carbon sources]]}},
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| {{SubtiWiki category|[[transcription factors and their control]]}},
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| {{SubtiWiki category|[[membrane proteins]]}}
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|
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[YesS regulon]]}}
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| =The [[YesS regulon]]:=
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| * ''[[yesS]]-[[yesT]]-[[yesU]]-[[yesV]]-[[yesW]]-[[yesX]]-[[yesY]]-[[yesZ]]''
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU07010
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU07010&redirect=T BSU07010]
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| * '''DBTBS entry:''' no entry
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12853]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:'''
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''[[Domains]]:''' [[PtsH|HPr]]-binding domain: aa 406 - 510 {{PubMed|19651770}}
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| * '''Modification:'''
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| * '''[[Cofactors]]:'''
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| * '''Effectors of protein activity:''' interaction with [[PtsH|HPr(His)-P]] (occurs in the absence of preferred carbon sources) stimulates YesS activity {{PubMed|19651770}}
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| * '''[[SubtInteract|Interactions]]:'''
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| ** [[YesS]] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [[SubtInteract|interactions]] {{PubMed|21630458}}
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| ** [[PtsH|HPr(His)-P]]-[[YesS]] {{PubMed|19651770}}
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| * '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
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|
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| === Database entries ===
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| * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU07010&redirect=T BSU07010]
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/O31522 O31522]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU07010]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''[[yesS]]-[[yesT]]-[[yesU]]-[[yesV]]-[[yesW]]-[[yesX]]-[[yesY]]-[[yesZ]]'' {{PubMed|19651770}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yesS_765838_768123_1 yesS] {{PubMed|22383849}}
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| * '''[[Sigma factor]]:'''
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| * '''Regulation:''' induced by pectin ([[YesS]]) {{PubMed|19651770}}
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| * '''Regulatory mechanism:''' [[YesS]]: transcriptional activation {{PubMed|19651770}}
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed> 19651770 17449691 21630458 24391637 </pubmed>
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| [[Category:Protein-coding genes]]
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