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* '''Description:''' germination (cortex hydrolysis) and sporulation <br/><br/>
{{#bank: GerM}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''gerM''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || germination (cortex hydrolysis) and sporulation
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28380 gerM]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 39 kDa, 4.683 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1098 bp, 366 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rph]]'', ''[[racE]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU28380 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU28380 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU28380 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:gerM_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=gerM_2902002_2903102_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:gerM_expression.png|500px]]
|-
|}
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[germination]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[SigE regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU28380
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/gerM.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10356]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:'''
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
* '''[[Localization]]:'''
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/P39072 P39072]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU28380]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''gerM'' {{PubMed|8969504}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=gerM_2902002_2903102_-1 gerM] {{PubMed|22383849}}
* '''Sigma factor:''' [[SigE]] {{PubMed|8969504,15699190}}
* '''Regulation:'''
** expressed early during sporulation in the mother cell ([[SigE]], [[SpoIIID]]) {{PubMed|8969504,15699190,15383836}}
** repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed] 
* '''Regulatory mechanism:'''
** [[SpoIIID]]: transcription repression {{PubMed|15383836}}
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>7926687,15699190,12107147, 8969504,15699190,15383836 18562273 </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 14:26, 2 April 2014