|
|
| (8 intermediate revisions by 3 users not shown) |
| Line 1: |
Line 1: |
| * '''Description:''' CDP-glycerol:polyglycerol phosphate glycero-phosphotransferase <br/><br/>
| | {{#bank: TagF}} |
|
| |
|
| {| align="right" border="1" cellpadding="2"
| |
| |-
| |
| |style="background:#ABCDEF;" align="center"|'''Gene name'''
| |
| |''tagF''
| |
| |-
| |
| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''rodC ''
| |
| |-
| |
| |style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
| |
| |-
| |
| |style="background:#ABCDEF;" align="center"| '''Product''' || CDP-glycerol:polyglycerol phosphate glycero-phosphotransferase
| |
| |-
| |
| |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of teichoic acid
| |
| |-
| |
| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU35720 tagF]
| |
| |-
| |
| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 87 kDa, 9.4
| |
| |-
| |
| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 2238 bp, 746 aa
| |
| |-
| |
| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[tagG]]'', ''[[tagE]]''
| |
| |-
| |
| |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15589]+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
| |
| |-
| |
| |colspan="2" | '''Genetic context''' <br/> [[Image:tagF_context.gif]]
| |
| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
| |
| |-
| |
| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tagF_3676159_3678399_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:tagF_expression.png|500px]]
| |
| |-
| |
| |}
| |
|
| |
| __TOC__
| |
| <br/><br/><br/><br/>
| |
| <br/><br/><br/><br/>
| |
| <br/><br/><br/><br/>
| |
| <br/><br/>
| |
|
| |
| = [[Categories]] containing this gene/protein =
| |
| {{SubtiWiki category|[[cell wall synthesis]]}},
| |
| {{SubtiWiki category|[[biosynthesis of cell wall components]]}},
| |
| {{SubtiWiki category|[[essential genes]]}},
| |
| {{SubtiWiki category|[[membrane proteins]]}}
| |
|
| |
| = This gene is a member of the following [[regulons]] =
| |
| {{SubtiWiki regulon|[[PhoP regulon]]}},
| |
| {{SubtiWiki regulon|[[WalR regulon]]}}
| |
|
| |
| =The gene=
| |
|
| |
| === Basic information ===
| |
|
| |
| * '''Locus tag:''' BSU35720
| |
|
| |
| ===Phenotypes of a mutant ===
| |
|
| |
| essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
| |
|
| |
| === Database entries ===
| |
|
| |
| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/tagDEF.html]
| |
|
| |
| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10725]
| |
|
| |
| === Additional information===
| |
|
| |
|
| |
|
| |
|
| |
| =The protein=
| |
|
| |
| === Basic information/ Evolution ===
| |
|
| |
| * '''Catalyzed reaction/ biological activity:''' CDP-glycerol + (glycerophosphate)(n) = CMP + (glycerophosphate)(n+1) (according to Swiss-Prot)
| |
|
| |
| * '''Protein family:''' CDP-glycerol glycerophosphotransferase family (according to Swiss-Prot)
| |
|
| |
| * '''Paralogous protein(s):'''
| |
|
| |
| === Extended information on the protein ===
| |
|
| |
| * '''Kinetic information:'''
| |
|
| |
| * '''Domains:'''
| |
|
| |
| * '''Modification:'''
| |
|
| |
| * '''Cofactor(s):'''
| |
|
| |
| * '''Effectors of protein activity:'''
| |
|
| |
| * '''[[SubtInteract|Interactions]]:'''
| |
|
| |
| * '''[[Localization]]:'''
| |
| ** membrane associated [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
| |
|
| |
| === Database entries ===
| |
|
| |
| * '''Structure:'''
| |
|
| |
| * '''UniProt:''' [http://www.uniprot.org/uniprot/P13485 P13485]
| |
|
| |
| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU35720]
| |
|
| |
| * '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.8.12 2.7.8.12]
| |
|
| |
| === Additional information===
| |
|
| |
| =Expression and regulation=
| |
| * '''Operon:''' ''[[tagD]]-[[tagE]]-[[tagF]]'' {{PubMed|2507871}}
| |
|
| |
| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tagF_3676159_3678399_-1 tagF] {{PubMed|22383849}}
| |
|
| |
| * '''Sigma factor:''' [[SigA]] {{PubMed|7581998}}
| |
|
| |
| * '''Regulation:'''
| |
| ** repressed by phosphate ([[PhoP]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9457886 PubMed]
| |
| ** strongly repressed in response to glucose starvation in M9 medium {{PubMed|23033921}}
| |
|
| |
| * '''Regulatory mechanism:'''
| |
| ** [[PhoP]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/9457886 PubMed]
| |
| ** [[WalR]]: transcription activation {{PubMed|12950927}}
| |
|
| |
| * '''Additional information:'''
| |
|
| |
| =Biological materials =
| |
|
| |
| * '''Mutant:'''
| |
|
| |
| * '''Expression vector:'''
| |
|
| |
| * '''lacZ fusion:'''
| |
|
| |
| * '''GFP fusion:'''
| |
|
| |
| * '''two-hybrid system:'''
| |
|
| |
| * '''Antibody:'''
| |
|
| |
| =Labs working on this gene/protein=
| |
|
| |
| =Your additional remarks=
| |
|
| |
| =References=
| |
| '''Additional publications:''' {{PubMed|23033921}}
| |
| <pubmed>18156271,16141206 2507871 ,12637499,1712357,9457886,18763711, 19520862 7581998 12950927 15547257 </pubmed>
| |
|
| |
| [[Category:Protein-coding genes]]
| |
