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| | {{#bank: FbpB}} |
| * '''Description:''' Fur-regulated basic protein, acts as RNA chaperone for ''[[fsrA]]'', response to iron limitation <br/><br/>
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| {| align="right" border="1" cellpadding="2" | |
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''fbpB''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ydbN''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || Fur-regulated basic protein, acts as RNA chaperone<br/> for ''[[fsrA]]'', response to iron limitation
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| |style="background:#ABCDEF;" align="center"|'''Function''' || RNA chaperone
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU04530 fbpB]
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 6 kDa, 9.9
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 177 bp, 59 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ydbM]]'', ''[[fbpA]]''
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| |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12260]+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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| |colspan="2" | '''Genetic context''' <br/> [[Image:FbpA_fbpB_context.jpeg]]
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| |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ydbN_506322_506501_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:fbpB_expression.png|500px]]
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| |}
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| __TOC__
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/><br/><br/>
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[acquisition of iron]]}},
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| {{SubtiWiki category|[[iron metabolism]]}},
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| {{SubtiWiki category|[[RNA chaperones]]}},
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| {{SubtiWiki category|[[short peptides]]}}
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|
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[Fur regulon]]}}
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| =The [[FbpB regulon]]: ''[[lutA]]-[[lutB]]-[[lutC]]''=
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU04530
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| ===Phenotypes of a mutant ===
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| * transcription profile of a ''[[fbpA]] [[fbpB]]'' double mutant strain: [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27416 GEO] {{PubMed|22389480}}
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| === Database entries ===
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ydbN.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12081]
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| * '''GEO entry:''' [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27416 GEO] {{PubMed|22389480}}
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| === Additional information===
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| The sequence of the former ydbN gene was corrected, and does now contain two genes, [[fbpA]] and [[fbpB]]. [http://www.ncbi.nlm.nih.gov/sites/entrez/18697947 PubMed]
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:'''
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| * '''[[Localization]]:'''
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| === Database entries ===
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/P96609 P96609]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU04530]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''[[fbpA]]-[[fbpB]]'' {{PubMed|18697947}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ydbN_506322_506501_-1 fbpB] {{PubMed|22383849}}
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| * '''Sigma factor:'''
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| * '''Regulation:'''
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| ** induced upon iron starvation ([[Fur]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]
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| * '''Regulatory mechanism:'''
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| ** [[Fur]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]
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| * '''Additional information:'''
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| ** The mRNA has a long 5' leader region. This may indicate RNA-based regulation {{PubMed|20525796}}
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed>12354229,18697947, 20525796 22389480 22427629</pubmed>
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| [[Category:Protein-coding genes]]
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