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* '''Description:''' polysaccharide deacetylase <br/><br/>
{{#bank: PdaB}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''pdaB''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ybaN''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || polysaccharide deacetylase
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || spore cortex formation
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 28 kDa, 9.182 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 762 bp, 254 aa
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[kbaA]]'', ''[[rrnI-16S]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB11933&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:ybaN_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybaN_159779_160543_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:pdaB_expression.png|500px]]
|-
|}
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[sporulation proteins]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[SigE regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU01570
===Phenotypes of a mutant ===
''[[pdaB]] [[ytrI]]'' and ''[[pdaB]] [[ytrH]]'' mutants are deficient in sporulation
=== Database entries ===
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ybaN.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11416]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' polysaccharide deacetylase family (according to Swiss-Prot)
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
* '''[[Localization]]:''' forespore (according to Swiss-Prot)
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/P50865 P50865]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU01570]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' '''pdaB''' [http://www.ncbi.nlm.nih.gov/sites/entrez/12662922 PubMed]
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybaN_159779_160543_-1 pdaB] {{PubMed|22383849}}
* '''Sigma factor:''' [[SigE]] {{PubMed|15699190,12662922}}
* '''Regulation:''' expressed during sporulation in the mother cell [http://www.ncbi.nlm.nih.gov/sites/entrez/12662922 PubMed]
* '''Regulatory mechanism:''' [[SpoIIID]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12662922 PubMed]
* '''Additional information:'''  the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>12662922,12884008,15547282,15598884 , </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 12:51, 2 April 2014