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* '''Description:''' branched-chain amino acid transport <br/><br/>
{{#bank: AzlD}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''azlD''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yrdI ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || branched-chain amino acid transport
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU26700 azlD]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_synthesis.html Lipid synthesis], [http://subtiwiki.uni-goettingen.de/pathways/ile_val_leu.html Ile, Leu, Val]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 9.962 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 330 bp, 110 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[brnQ]]'', ''[[azlC]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14611&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:azlD_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=azlD_2728647_2728979_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:azlD_expression.png|500px]]
|-
|}
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[transporters/ other]]}},
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}},
{{SubtiWiki category|[[utilization of amino acids]]}},
{{SubtiWiki category|[[membrane proteins]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[AzlB regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU26700
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' no entry
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11916]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' azlD/HI1737/HP1330 family (according to Swiss-Prot)
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/O07923 O07923]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU26700]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[azlB]]-[[azlC]]-[[azlD]]-[[brnQ]]-[[yrdK]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9287000 PubMed]
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=azlD_2728647_2728979_-1 azlD] {{PubMed|22383849}}
* '''Sigma factor:'''
* '''Regulation:''' repressed by [[AzlB]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9287000 PubMed]
* '''Regulatory mechanism:''' [[AzlB]]: transcriptional repression [http://www.ncbi.nlm.nih.gov/sites/entrez/9287000 PubMed]
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>9287000,, </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 14:19, 2 April 2014