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{{#bank: SbcD}}


{| align="right" border="1" cellpadding="2"
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|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''sbcD''
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yixA ''
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no
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|style="background:#ABCDEF;" align="center"| '''Product''' || exonuclease SbcD homolog
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|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU10640 sbcD]
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 5.003 
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1173 bp, 391 aa
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[addA]]'', ''[[sbcC]]''
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12904&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|-
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|colspan="2" | '''Genetic context''' <br/> [[Image:sbcD_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sbcD_1143577_1144752_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:sbcD_expression.png|500px]]
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= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[DNA repair/ recombination]]}},
{{SubtiWiki category|[[genetic competence]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[ComK regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU10640
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/sbcD-yirY-yisB.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10467]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' sbcD family (according to Swiss-Prot)
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
* '''[[Localization]]:''' Cytoplasm (Homogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed]
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/P23479 P23479]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU10640]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[sbcD]]-[[sbcC]]-[[yisB]]'' (according to [http://dbtbs.hgc.jp/COG/prom/sbcD-yirY-yisB.html DBTBS])
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sbcD_1143577_1144752_1 sbcD] {{PubMed|22383849}}
* '''Sigma factor:'''
* '''Regulation:'''
** positive regulation by [[ComK]] {{PubMed|11948146}}
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
** GP894 (''sbcCD''::''kan''), available in [[Stülke]] lab
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>8493111,11948146 , 16479537</pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 10:02, 17 April 2014