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| * '''Description:''' [[ABC transporter]] (permease) for the export of lipid II-binding lantibiotics, such as nisin and gallidermin<br/><br/>
| | {{#bank: PsdB}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''psdB''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yvcS ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || [[ABC transporter]] (permease)
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| |-
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| |style="background:#ABCDEF;" align="center"|'''Function''' || export of toxic peptides
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/PsdB PsdB]
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 73 kDa, 9.804
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1938 bp, 646 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yvcT]]'', ''[[psdA]]''
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| |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15474]+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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| |colspan="2" | '''Genetic context''' <br/> [[Image:yvcS_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |-
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| |}
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| __TOC__
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[ABC transporters]]}},
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| {{SubtiWiki category|[[resistance against toxins/ antibiotics]]}},
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| {{SubtiWiki category|[[membrane proteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[PsdR regulon]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU34690
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''DBTBS entry:''' no entry
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12408]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:''' ABC-4 integral membrane protein family (according to Swiss-Prot)
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| ** [[PsdA]]-[[PsdB]] {{PubMed|10092453}}
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| * '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
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| === Database entries ===
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/O06981 O06981]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU34690]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:'''
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| ** ''[[psdA]]-[[psdB]]'' {{PubMed|18394148}}
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| ** ''[[psdR]]-[[psdS]]-[[psdA]]-[[psdB]]'' {{PubMed|21078927}}
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvcS_3563581_3565521_-1 psdB] {{PubMed|22383849}}
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| * '''Sigma factor:'''
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| ** ''[[psdA]]'': [[SigA]] {{PubMed|21078927}}
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| ** ''[[psdR]]'': [[SigA]] {{PubMed|21078927}}
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| * '''Regulation:'''
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| ** ''[[psdA]]'': induced by nisin, gallidermin ([[PsdR]]) {{PubMed|21078927}}
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| * '''Regulatory mechanism:'''
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| ** [[PsdR]]: transcription activation {{PubMed|21078927}}
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| '''Additional publications:''' {{PubMed|21078927}}
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| <pubmed>18394148,10092453, 21283517</pubmed>
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| [[Category:Protein-coding genes]]
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