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* '''Description:''' late competence gene <br/><br/>
{{#bank: ComZ}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''comZ''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yjzA ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || compentence
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]'''
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 7 kDa, 4.37 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 189 bp, 63 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[med]]'', ''[[yjzB]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12972&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:comZ_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|}
__TOC__
<br/><br/>
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[genetic competence]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[Spo0A regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU11310
[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comZ_1207597_1207788_1 Expression]
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/med-comZ.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13221]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:'''
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''[[SubtInteract|Interactions]]:'''
* '''[[Localization]]:'''
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/O32437 O32437]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU11310]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[med]]-[[comZ]]'' {{PubMed|9335269}}
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9335269}}
* '''Regulation:'''
** repressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed]
* '''Regulatory mechanism:'''
** [[Spo0A]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed]
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>10940045,9335269, 14651647 </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 11:46, 8 April 2014