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| * '''Description:''' required for processing and compartmentalization of pro-[[SigE]] <br/><br/>
| | {{#bank: SpoIIR}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''spoIIR''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ipc-27d, csfX ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || morphological chekcpoint for [[SigE]] processing
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| |-
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| |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigE]] activation
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 25 kDa, 4.737
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 672 bp, 224 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywlB]]'', ''[[ywlA]]''
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| |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15714]+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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| |colspan="2" | '''Genetic context''' <br/> [[Image:spoIIR_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |-
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| |}
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| __TOC__
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[sigma factors and their control]]}},
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| {{SubtiWiki category|[[sporulation proteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[SigF regulon]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU36970
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoIIR.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10937]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:'''
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| * '''[[Localization]]:'''
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| ** localizes initially to the forespore septal membrane, is then exported to the intermembrane space between the forespore and the mother cell {{PubMed|22111992}}
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| === Database entries ===
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/P39151 P39151]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU36970]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' spoIIR (according to [http://dbtbs.hgc.jp/COG/prom/spoIIR.html DBTBS])
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| * '''[[Sigma factor]]:''' [[SigF]] {{PubMed|16497325}}
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| * '''Regulation:'''
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| ** expressed early during sporulation in the forespore ([[SigF]]) {{PubMed|16497325,15699190}}
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| * '''Regulatory mechanism:'''
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| <pubmed>16497325,7585939,15044948,11849534, 19578359 20802044 22111992 </pubmed>
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| [[Category:Protein-coding genes]]
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