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| * '''Description:''' class III heat-shock protein (molecular chaperone) <br/><br/>
| | {{#bank: HtpG}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''htpG''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yxbB ''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |-
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| |style="background:#ABCDEF;" align="center"| '''Product''' || class III heat-shock protein (molecular chaperone)
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| |-
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| |style="background:#ABCDEF;" align="center"|'''Function''' || chaperone
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| |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
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| |-
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 72 kDa, 4.668
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1878 bp, 626 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[csbC]]'', ''[[yxcA]]''
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| |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB16018]+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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| |colspan="2" | '''Genetic context''' <br/> [[Image:htpG_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |-
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| |}
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| __TOC__
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| <br/><br/><br/><br/><br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[chaperones/ protein folding]]}},
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| {{SubtiWiki category|[[heat shock proteins]]}}
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| = This gene is a member of the following [[regulons]] =
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU39820
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/htpG.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11359]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:''' heat shock protein 90 family (according to Swiss-Prot)
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| * '''[[Localization]]:'''
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| ** cytoplasm (according to Swiss-Prot)
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| === Database entries ===
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| * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2IOQ 2IOQ] (from ''Escherichia coli'', 39% identity, 61% similarity) {{PubMed|17055434}}
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/P46208 P46208]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU39820]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''htpG'' {{PubMed|9150201}}
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| * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9150201}}
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| * '''Regulation:''' induced by high temperature {{PubMed|9150201}}
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| * '''Regulatory mechanism:''' unknown
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:''' GP1159 (del cat) available in the [[Stülke]] lab
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| [[Wolfgang Schumann]], Bayreuth University, Germany [http://www.genetik.uni-bayreuth.de/LSGenetik1/schumann_research.htm Homepage]
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| =Your additional remarks=
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| =References=
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| <pubmed>9150201,12511492,10323241,, </pubmed>
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| [[Category:Protein-coding genes]]
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