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* '''Description:''' negative regulator for ''[[lytA]]-[[lytB]]-[[lytC]]'' and ''[[lytR]]'' expression <br/><br/>
{{#bank: TagU}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''lytR''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || negative regulator for ''[[lytA]]-[[lytB]]-[[lytC]]'' and ''[[lytR]]'' expression
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of cell separation and autolysis
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 34 kDa, 9.527 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 918 bp, 306 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lytA]]'', ''[[mnaA]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15582&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:lytR_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|}
__TOC__
<br/><br/>
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[cell wall degradation/ turnover]]}},
{{SubtiWiki category|[[transcription factors and their control]]}},
{{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, V, W, X, Y)]]}},
{{SubtiWiki category|[[membrane proteins]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[LytR regulon]]}},
{{SubtiWiki regulon|[[SigX regulon]]}}
=The [[LytR regulon]]:=
* ''[[lytA]]-[[lytB]]-[[lytC]]'', ''[[lytR]]''
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU35650
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/lytR.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10404]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:'''
* '''Protein family:''' lytR/cpsA/psr regulatory protein family (according to Swiss-Prot)
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''Interactions:'''
* '''Localization:''' cell membrane (according to Swiss-Prot)
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/Q02115 Q02115]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU35650]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''lytR'' {{PubMed|1357079}}
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|1357079,9636707}}, [[SigX]] {{PubMed|1357079,9636707}}
* '''Regulation:'''
* '''Regulatory mechanism:'''
** [[LytR]]: autorepression {{PubMed|1357079}}
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>9636707,1357079 , </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 11:45, 19 June 2014