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* '''Description:''' [[response regulator aspartate phosphatase]], controls [[ComA]] activity <br/><br/>
{{#bank: RapK}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''rapK''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yobG ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || [[response regulator aspartate phosphatase]]
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[ComA]] activity
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 5.06 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1113 bp, 371 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yozJ]]'', ''[[phrK]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13783&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:rapK_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|}
__TOC__
<br/><br/>
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[genetic competence]]}},
{{SubtiWiki category|[[protein modification]]}},
{{SubtiWiki category|[[transcription factors and their control]]}},
{{SubtiWiki category|[[quorum sensing]]}}
= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[SigH regulon]]}}
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU18910
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/rapK-phrK.html]
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12664]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:''' control of [[ComA]] activity {{PubMed|16816200}}
* '''Protein family:'''
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:''' binding of [[PhrK]] inhibits RapK activity {{PubMed|16816200}}
* '''Interactions:''' [[RapK]]-[[PhrK]] {{PubMed|16816200}}
* '''Localization:'''
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/O34930 O34930]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU18910]
* '''E.C. number:'''
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[rapK]]-[[phrK]]'' {{PubMed|11466295}}
* '''[[Sigma factor]]:''' [[SigH]] {{PubMed|11466295}}
* '''Regulation:'''
* '''Regulatory mechanism:'''
** [[AbrB]]: transcription repression {{PubMed|20817675}}
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed> 11466295 16816200 20817675</pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 13:06, 11 February 2015