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| Biofilms are the result of the multicellular lifestyle of ''B. subtilis''. They are characterized by the formation of a matrix polysaccharide and an amyloid-like protein, [[TasA]].
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| {CategoryTree
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| |Parents=
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| * 4. [[Life styles]]
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| ** 4.2 [[Processes activated during stationary phase]]
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| |Neighbors=
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| * 4.2.1 [[Sporulation and germination]]
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| * 4.2.3 [[Coping with stress]]
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| * 4.2.4 [[Life styles -- miscellaneous]]
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| |Related=
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| no
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| |}
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| __TOC__
| | [[File:Example.jpg]] |
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| ==[http://subtiwiki.uni-goettingen.de/pathways/biofilm.html Biofilm formation in ''Subti''Pathways]==
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| ==Labs working on biofilm formation==
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| * [[Daniel Kearns]]
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| * [[Oscar Kuipers]]
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| * [[Beth Lazazzera]]
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| * [[Richard Losick]]
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| * [[Nicola Stanley-Wall]]
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| ==Key genes and operons involved in biofilm formation==
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| * matrix polysaccharide synthesis:
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| ** ''[[epsA]]-[[epsB]]-[[epsC]]-[[epsD]]-[[epsE]]-[[epsF]]-[[epsG]]-[[epsH]]-[[epsI]]-[[epsJ]]-[[epsK]]-[[epsL]]-[[epsM]]-[[epsN]]-[[epsO]]''
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| * amyloid protein synthesis
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| ** ''[[yqxM]]-[[sipW]]-[[tasA]]''
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| * regulation
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| ** [[SlrR]]
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| ** [[SlrA]]
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| ** [[SinR]]
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| ** [[SinI]]
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| ** [[PtkA]]
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| ** [[TkmA]]
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| ** [[PtpZ]]
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| ** [[DegU]]
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| ** [[RacX]]
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| * biofilm disassembly
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| ** [[YlmE]]
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| * other proteins required for biofilm formation
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| ** [[SpeA]]
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| ** [[YmcA]]
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| ** [[YxaB]]
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| ==Key reviews==
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| <pubmed>19054118 19054118 16787201 9891794 20890834 </pubmed>
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| * additional reviews: {{PubMed|20735481}}
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